Reduced efficacy of single-dose albendazole against Ascaris lumbricoides, and Trichuris trichiura, and high reinfection rate after cure among school children in southern Ethiopia: a prospective cohort study

Table 3 Factors associated with cure rates for each STH infections at week 4 post single dose albendazole mass drug administration

Variables	Hookworm			Ascaris lumbricoides			Trichuris trichiura
Variables	Total n	Cure rate (%)	P	Total n	Cure rate (%)	P	Total n	Cure rate (%)	P
Age group
≤ 9 years	33	100	0.25	225	64.4	0.006	107	46.7	0.52
≥ 10 years	76	96.1	0.25	589	74.2	0.006	348	50.3	0.52
Sex
Male	63	96.8	0.75	403	71.2	0.86	219	47.5	0.42
Female	46	97.8	0.75	411	71.8	0.86	236	51.3	0.42
Coinfection with Schistosoma mansoni
No coinfection	70	95.7	0.19	576	70.8	0.51	288	49.3	0.94
With coinfection	39	100	0.19	238	73.1	0.51	167	49.7	0.94
Number of STH infections at baseline
Single infection	34	94.1	0.28	456	69.5	0.29	127	54.3	0.15
Double infection	45	100		329	73.6		299	48.8
Triple infection	30	96.7		29	79.3		29	34.5
Coinfection with other STH parasites
Yes	86	98.8	0.05	467	73.7	0.11	375	49.6	0.89
No	23	91.3	0.05	347	68.6	0.11	80	48.8	0.89
Pretreatment infection intensity
Light	109	97.2		550	73.5	0.19	441	50.1	0.11
Moderate				240	67.1		14	28.6
Heavy				24	70.8

ISSN: 2049-9957