Immediate and long-term outcomes after treat-all among people living with HIV in China: an interrupted time series analysis

Table 5 Sensitivity analyses accounting for seasonality in the analysis of the impact of treat-all on three indicators of ART among PLHIV in China 1 January 2015 to 31 December 2019^#

	IRR (95% CI)
	Level change at treat-all	P value	Level change in December 2019	P value	Trend before treat-all	P value	Trend after treat-all	P value
Proportion of 30-day ART initiation*	1.116 (1.057–1.179)	< 0.001	1.006 (0.727–1.394)	0.969	1.011 (1.004–1.017)	0.002	1.008 (1.007–1.009)	< 0.001
Mean CD4^†	0.996 (0.995–1.038)	0.844	1.002 (0.876–1.146)	0.979	0.997 (0.995–1.000)	0.056	0.997 (0.997–0.998)	< 0.001
Mean estimated time to diagnosis^†	1.070 (1.024–1.118)	0.002	0.970 (0.856–1.099)	0.646	1.004 (1.001–1.006)	0.002	1.001 (1.000–1.003)	0.043

IRR Incidence rate ratio, CI Confidence interval, ART Antiretroviral therapy. Treat-all: June 2016. PLHIV: People living with HIV. #: three indicators include proportion of 30-day ART initiation, mean CD4 counts (cells/μL) at ART initiation, and mean estimated time from infection to diagnosis (year). *: using quasi-Poisson segmented regression models. †: using Poisson segmented regression models

ISSN: 2049-9957