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Table 1 Univariate analysis with logistic regression for Blastocystis hominis infection in persons living with human immunodeficiency virus

From: Impact factors of Blastocystis hominis infection in persons living with human immunodeficiency virus: a large-scale, multi-center observational study from China

Variables

Subgroups

Total

n (%)

Blastocystis hominis

negative

N = 1184

n (%)

Blastocystis hominis

positive

N = 61

n (%)

Univariate analysis

Wald χ2

P value

OR (95% CIs)

Age

< 60 years

1104 (88.7)

1051 (88.8)

53 (86.9)

0.204

0.651

1 (reference)

 

≥ 60 years

141 (11.3)

133 (11.2)

8 (13.1)

1.193 (0.555–2.563)

BMI

Normal weight (18.5–24.9 kg/m2)

1143 (91.8)

1084 (91.6)

59 (96.7)

1.593

0.451

1 (reference)

 

Low weight (< 18.5 kg/m2)

94 (7.6)

92 (7.8)

2 (3.3)

0.399 (0.096–1.661)

 

Over weight (≥ 25.0 kg/m2)

8 (0.6)

8 (0.7)

0 (0.0)

Family members

< 3 individuals

382 (30.7)

368 (31.1)

14 (23.0)

1.780

0.182

1 (reference)

 

≥ 3 individuals

863 (69.3)

816 (68.9)

47 (77.0)

1.514 (0.823–2.785)

Gender

Male

793 (63.7)

756 (63.9)

37 (60.7)

0.256

0.613

1 (reference)

 

Female

452 (36.3)

428 (36.1)

24 (39.3)

1.146 (0.676–1.941)

Residence

Rural area

939 (75.4)

893 (75.4)

46 (75.4)

0.001

0.998

1 (reference)

 

Urban area

306 (24.6)

291 (24.6)

15 (24.6)

1.001 (0.551–1.819)

Region

Nanchang city

411 (33.0)

387 (32.7)

24 (39.3)

1.163

0.559

1 (reference)

 

Fuyang city

479 (38.5)

458 (38.7)

21 (34.4)

0.739 (0.405–1.349)

 

Tengchong city

355 (28.5)

339 (28.6)

16 (22.2)

0.761 (0.398–1.457)

Occupation

Student

50 (4.0)

48 (4.1)

2 (3.3)

3.731

0.292

1 (reference)

 

Farmer

877 (70.4)

835 (70.5)

42 (68.9)

1.207 (0.284–5.136)

 

Other occupation

195 (15.7)

181 (15.3)

14 (23.0)

1.856 (0.408–8.449)

 

Worker

123 (9.9)

120 (10.1)

3 (4.9)

0.600 (0.097–3.704)

Nationality

Han nationality

1207 (96.9)

1148 (97.0)

59 (96.7)

0.011

0.916

1 (reference)

 

Minority nationality

38 (3.1)

36 (3.0)

2 (3.3)

1.081 (0.254–4.598)

Marital status

Single

320 (25.7)

307 (25.9)

13 (21.3)

0.645

0.422

1 (reference)

 

Married

925 (74.3)

877 (74.1)

48 (78.7)

1.293 (0.691–2.418)

Educational level

High school or below

1163 (93.4)

1105 (93.3)

58 (95.1)

0.288

0.592

1 (reference)

 

University or above

82 (6.6)

79 (6.7)

3 (4.9)

0.723 (0.222–2.361)

Toilet type

Flush toilet

860 (69.1)

818 (69.1)

42 (68.9)

0.002

0.969

1 (reference)

 

Non-flush toilet

385 (30.9)

366 (30.9)

19 (31.1)

1.011 (0.580–1.762)

Water supply

Tap water

760 (61.0)

721 (60.9)

39 (63.9)

0.225

0.636

1 (reference)

 

Non tap water

485 (39.0)

463 (39.1)

22 (36.1)

0.878 (0.514–1.501)

Drinking water

Boiled water

1199 (96.3)

1140 (96.3)

59 (96.7)

0.031

0.861

1 (reference)

 

Non-boiled water

46 (3.7)

44 (3.7)

2 (3.3)

0.878 (0.208–3.711)

Livestock

No

975 (78.3)

930 (78.5)

45 (73.8)

0.775

0.379

1 (reference)

 

Yes

270 (21.7)

254 (21.5)

16 (26.2)

1.302 (0.724–2.342)

Pet

No

1108 (89.0)

1051 (88.8)

57 (93.4)

1.259

0.262

1 (reference)

 

Yes

137 (11.0)

133 (11.2)

4 (6.6)

0.555 (0.198–1.553)

Newly infection

No (≥ 2 years)

1138 (91.4)

1079 (91.1)

59 (96.7)

2.109

0.146

1 (reference)

 

Yes (< 2 years)

107 (8.6)

105 (8.9)

2 (3.3)

0.348 (0.084–1.446)

HIV infection route

Sexually transmission

815 (65.5)

778 (65.7)

37 (60.7)

0.685

0.710

1 (reference)

 

Transmission among injectors

40 (3.2)

38 (3.2)

2 (3.3)

1.107 (0.257–4.764)

 

Blood transmission

390 (31.3)

368 (31.1)

22 (36.1)

1.257 (0.731–2.162)

CD4+ T immunological status

No immunosuppression (> 500 cells/μl)

628 (50.4)

625 (52.8)

3 (4.9)

71.388

< 0.001

1 (reference)

 

Mild immunosuppression (350–500 cells/μl)

411 (33.0)

396 (33.4)

15 (24.6)

7.891 (2.270–27.433)

 

Moderate immunosuppression

(200–350 cells/μl)

104 (8.4)

83 (7.0)

21 (34.4)

52.711 (15.389–180.552)

 

Severe immunosuppression

(≤ 200 cells/μl)

102 (8.2)

80 (6.8)

22 (36.1)

52.711 (15.389–180.552)

HIV virological status

Full virological suppression (< 50 copies/ml)

972 (78.1)

968 (81.8)

4 (6.6)

69.345

< 0.001

1 (reference)

 

Low level viraemia (51–999 copies/ml)

92 (7.4)

80 (6.8)

12 (19.7)

36.300 (11.444–115.140)

 

Virological failure (> 1000 copies/ml)

181 (14.5)

136 (11.5)

45 (73.8)

80.074 (28.352–226.147)

Treatment interruption

No

1114 (89.5)

1087 (91.8)

27 (44.3)

90.201

< 0.001

1 (reference)

 

Yes

131 (10.5)

97 (8.2)

34 (55.7)

14.111 (8.172–24.367)

  1. The “–” symbol indicates that data could not be calculated. BMI: Body mass index. CIs: Confidence intervals. HIV: Human immunodeficiency virus. OR: Odds ratio