From: Research gaps for three main tropical diseases in the People’s Republic of China
Disease | Immunodiagnosis method Research in field survey | Development of immunodiagnosis kit | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Disease | Total | Type (n) | Sensitivity | Specificity | Population | Total | Leading research direction | Labwork | Human test (n) | Basic Science | Marketization |
Malaria | 26* | GICA(9) | 88.4-95.5% | 95.7-100% | 547 | 35 | GICA (9) | 16 | 19 | 11/35 | 24/35 |
ICA(14) | 74.2-98.6% | 91.3-100% | 938 | ||||||||
PCR(10) | 96.1-99.6% | 98.8-100% | 167 | ||||||||
LAMP(2) | 98.3-98.8% | 100% | 46 | ||||||||
Schistosomiasis | 55* | COPT(3) | 90.0-91.8% | 95.3-97.4% | 89 | 52 | Candidate Recombination Protein Finding (28) | 41 | 11 | 44/52 | 8/52 |
DDIA(8) | 75.3-97.1% | 55.1-99.0% | 755 | ||||||||
DIGFA(9) | 92.0-100% | 92.2-97.5% | 556 | ||||||||
ELISA(25) | 65.8-98.4% | 51.7-100% | 716 | ||||||||
IHA(32) | 69.6-97.3% | 63.6-97.8% | 743 | ||||||||
PCR(4) | 100% | 100% | 52 | ||||||||
Others(6) | 85.5-98.5% | 76.3-97.0% | 85 | ||||||||
Echinococcosis | 9* | IHA(4) | 87.1-92.7% | 69.5-91.6% | 315 | 24 | DIGFA (6) | 8 | 16 | 5/24 | 19/24 |
DIGFA(2) | 56.7-93.2% | 79.1-95.0% | 180 | ||||||||
ELISA(8) | 59.3%-91.2% | 93.8-100% | 289 | ||||||||
Others(3) | 32.5%-76.9% | 41.3-81.6% | 42 |