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Table 5 Summary estimates for the overall and subgroup analysis for school-based, non-integrated, and integrated delivery strategies

From: Community-based interventions for the prevention and control of helmintic neglected tropical diseases

Outcomes Estimates (95% CI)
  Combined School-based delivery Community-based non-integrated delivery Community-based integrated delivery
STH Prevalence (RR) 0.45 [0.38, 0.54] 0.49 [0.39, 0.63] 0.52 [0.41, 0.67] 0.30 [0.12, 0.78]
45 datasets, 12 studies 19 datasets from 6 studies 16 datasets from 4 studies 9 datasets from 1 study
Hookworm 0.38 [0.27, 0.53] 0.37 [0.22, 0.62] 0.49 [0.29, 0.85] 0.25 [0.04, 1.62]
15 datasets, 10 studies 7 datasets from 5 studies 5 datasets from 3 studies 3 datasets from 1 study
Ascariasis 0.32 [0.19, 0.52] 0.28 [0.09, 0.89] 0.36 [0.18, 0.74] 0.28 [0.09, 0.87]
15 datasets, 9 studies 4 datasets from 6 studies 6 datasets from 4 studies 3 datasets from 1 studies
Trichuriasis 0.66 [0.53, 0.82] 0.78 [0.67, 0.90] 0.76 [0.62, 0.94] 0.41 [0.07, 2.56]
14 datasets, 8 studies 4 datasets from 6 studies 5 datasets from 3 study 3 datasets from 1 studies
Schistosomiasis Prevalence (RR) 0.40 [0.33, 0.50] 0.50 [0.33, 0.75] 0.42 [0.31, 0.57] 0.24 [0.11, 0.56]
25 datasets, 13 studies 7 datasets from 5 studies 12 datasets from 4 studies 6 datasets from 4 studies
S. H a ematobium 0.40 [0.29, 0.57] 0.59 [0.35, 1.02] 0.42 [0.26, 0.70] 0.05 [0.01, 0.45]
10 datasets, 8 studies 3 datasets from 3 studies 5 datasets from 3 studies 2 datasets from 2 studies
S. Japonicum 0.24 [0.06, 0.87] No studies 0.24 [0.06, 0.87] No studies
4 datasets, 2 studies 4 datasets from 2 studies
S. Mansoni 0.48 [0.35, 0.65] 0.44 [0.27, 0.74] 0.68 [0.42, 1.10] 0.38 [0.16, 0.91]
11 datasets, 7 studies 4 datasets from 4 studies 3 datasets from 1 study 4 datasets from 2 studies
STH intensity (SMD) −3.16 [−4.28, −2.04] −0.22 [−0.26, −0.17] −5.29 [−9.22, −1.36] No studies
5 datasets, 3 studies 2 datasets, 2 studies 3 datasets from 1 study
Hookworm −2.22 [−3.27, −1.17] −0.22 [−0.26, −0.17] −6.79 [−7.44, −6.14] No studies
3 datasets, 3 studies 2 datasets, 2 studies 1 dataset from 1 study
Ascariasis −7.25 [−7.93, −6.56] No studies −7.25 [−7.93, −6.56] No studies
1 dataset, 1 study 1 dataset from 1 study
Trichuriasis −1.87 [−2.16, −1.57] No studies −1.87 [−2.16, −1.57] No studies
1 dataset, 1 study 1 dataset from 1 study
Mean hemoglobin (SMD) 0.34 [0.20, 0.47] 0.24 [0.16, 0.32] 0.93 [−0.33, 2.18] 0.09 [−0.01, 0.20]
14 datasets, 12 studies 7 datasets from 7 studies 3 datasets from 3 studies 4 datasets from 2 studies
Anemia 0.90 [0.85, 0.96] 0.87 [0.81, 0.94] 0.85 [0.69, 1.06] 0.99 [0.90, 1.09]
9 datasets, 7 studies 5 datasets from 5 studies 1 datasets from 1 study 3 datasets from 1 study
Serum ferritin (SMD) 2.30 [−1.13, 5.73] 0.10 [−0.04, 0.25] No studies −0.01 [−0.36, 0.34]
4 datasets, 4 studies 3 datasets from 3 studies 1 dataset from 1 study
Height 0.01 [−0.10, 0.12] 0.04 [−0.08, 0.15] −0.19 [−0.53, 0.14] No studies
4 datasets, 4 studies 3 datasets from 3 studies 1 dataset from 1 study
Weight −0.13 [−0.42, 0.16] −0.09 [−0.46, 0.27] −0.27 [−0.60, 0.07] No studies
4 datasets, 4 studies 3 datasets from 3 studies 1 dataset from 1 study
Birth outcomes     
Birth weight −9.52 [−13.86, −5.19] No studies No studies −9.52 [−13.86, −5.19]
6 datasets, 3 studies 6 datasets from 3 studies
LBW 0.96 [0.78, 1.18] No studies No studies 0.96 [0.78, 1.18]
4 datasets, 2 studies 4 datasets from 2 studies
VLBW 0.38 [0.16, 0.87] No studies No studies 0.38 [0.16, 0.87]
4 datasets, 2 studies 4 datasets from 2 studies
Stillbirths 1.54 [0.93, 2.58] No studies No studies 1.54 [0.93, 2.58]
3 datasets, 1 study 3 datasets from 1 study
  1. *Estimates in bold are statistically significant.