Skip to main content

Table 2 Characteristics of the included studies

From: Community based interventions for the prevention and control of tuberculosis

Study Study design Country Intervention Target Population Integrated/Non-Integrated
Gandhi 2008 [38] Before/after South Africa DOTS therapy integrated with anti-retroviral therapy on a community level TB and HIV co-infected adults Integrated
Chaisson 2001 [37] RCT USA Preventive Isoniazid therapy for injection drug users Injection drug users Non-integrated
Zwarenstein 1998 [50] RCT South Africa Self-supervised treatment compared against therapy observed in clinic Adult pulmonary TB patients Non-integrated
Heal 1998 [39] Quasi-trial Canada Self-administered preventive therapy compared against preventive therapy observed in a clinic All aboriginals in British Columbia undergoing preventive therapy for TB Non-integrated
Kamolratanakul 1999 [40] RCT Thailand DOTS therapy compared against self-supervised therapy All smear positive pulmonary TB patients Non-integrated
Khan 2002 [41] RCT Pakistan DOTS therapy compared against self-supervised therapy Adults with TB Non-integrated
Lwilla 2003 [42] RCT Tanzania Community-based DOTS compared against institution-based DOTS All patients diagnosed with TB at selected health centres Non-integrated
MacIntyre 2003 [43] Quasi-trial Australia Family member supervised DOTS compared against non-observed therapy All patients diagnosed with TB at selected health centres Non-integrated
Malotte 2001 [44] RCT USA INH therapy of latent TB infections given either by outreach workers or at a facility People with active or recent history of drug use Non-integrated
Newell 2006 [45] RCT Nepal Comparison between community-members DOTS and family member DOTS All new smear positive cases of pulmonary TB Non-integrated
Ollé-Goig 2001 [46] Quasi-trial Haiti DOTS compared with non-observed therapy Adult TB patients Non-integrated
Walley 2001 [47] RCT Pakistan DOTS by family member compared with DOTS by healthcare worker and non-observed therapy Adult TB patients Non-integrated
Wandwalo 2004 [48] RCT Tanzania Community-based DOTS compared against healthcare worker DOTS TB patients of all ages Non-integrated
Wright 2004 [49] RCT Swaziland Community health worker DOTS compared with family member DOTS TB patients of all ages Non-integrated
Atkins 2011 [11] Quasi-trial South Africa Enhanced tuberculosis treatment adherence Adult TB patients Integrated
Barker 2002 [12] Quasi-trial South Africa Community-based DOTS compared against healthcare worker DOTS TB patients of all ages Non-integrated
Clarke 2005 [15] RCT South Africa Comparison between conventional TB treatment and lay health worker DOTS Adult TB patients Non-integrated
Colvin 2003 [16] Quasi-trial South Africa Traditional healers mobilized as DOTS supervisors TB patients of all ages Non-integrated
Corbett 2010 [17] RCT Zimbabwe Door-to-door and mobile van announcements compared as strategies to increase TB detection All people in a specific community Integrated
Diez 1996 [18] Before/after Spain Social support for deserving TB patients Adult TB patients Non-integrated
Dudley 2003 [19] Quasi-trial South Africa DOTS compared with non-observed therapy Adult TB patients Non-integrated
Fairall 2005 [20] RCT South Africa Educational outreach to nurses to increase TB case detection Patients attending specific clinics Integrated
Ferreira 2011 [21] Quasi-trial Brazil DOTS compared with non-observed therapy TB patients of all ages Non-integrated
Filho 2009 [14] Quasi-trial Brazil Food baskets offered to patient to assess effect on treatment outcomes Adult TB patients Integrated
Kamineni 2011 [22] Before/after India Increasing case detection and treatment adherence, decreasing stigma and discrimination, empowering affected people, and mobilising political commitment and resources TB patients of all ages Non-integrated
Kirondea 2002 [23] Quasi-trial South Africa Assessing the feasibility of using lay volunteers as DOTS supervisors Adult TB patients Non-integrated
Vieira 2011 [31] Quasi-trial Brazil DOTS compared with non-observed therapy Adult TB patients Non-integrated
Weis 1994 [32] Before/after USA DOTS compared with non-observed therapy TB patients of all ages Non-integrated
White 2002 [33] RCT USA Incentivized treatment compared with no incentive Susceptible population in a county jail Non-integrated
Zwarenstein 2000 [35] RCT South Africa DOTS compared with non-observed therapy TB patients of all ages Non-integrated
Prado 2011 [27] Quasi-trial Brazil Community health worker DOTS compared with family member DOTS Adult TB patients Non-integrated
Vassall 2002 [30] Quasi-trial Syria and Egypt Community-based DOTS compared against institution-based DOTS TB patients of all ages Integrated
CDI study group RCT Nigeria, Uganda and Cameroon Integration of community interventions to counter multiple diseases through a single framework TB patients of all ages Integrated
Miti 2003 [25] Quasi-trial Zambia Integration of HIV and TB services Adult TB patients Integrated
Amo-Adjei 2013 [10] Before/after Ghana Improvements in diagnosis, community TB care and stigma reduction among community and health workers towards TB patients Adult TB patients Integrated
Brust 2012 [13] Before/after South Africa Integration of HIV and TB services Adult TB patients Integrated
Mafigiri 2012 [24] Quasi-trial Uganda Community-based DOTS compared against institution-based DOTS TB patients of all ages Non-integrated
Niazi 2003 [26] Quasi-trial Iraq Community-based DOTS compared against institution-based DOTS Adult TB patients Non-integrated
Uwimana 2012 [28] RCT South Africa Training community care workers (CCWs) to provide integrated care All members of localities where the CCWs were based Integrated
Uwimana 2013 [29] Before/after South Africa Training community care workers (CCWs) to provide integrated care All members of localities where the CCWs were based Integrated
Yassin 2013 [34] Quasi-trial Ethiopia Training, engaging stakeholders and communities and active case-finding by female Health Extension Workers (HEWs) at village level All members of localities where the HEWs were based Non-integrated