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Table 3 Mean CD4 + Tcell count, viral load and haematologic parameters of study participants grouped by ART duration, regimen type and co-infection status

From: Immuno-haematologic and virologic responses and predictors of virologic failure in HIV-1 infected adults on first-line antiretroviral therapy in Cameroon

  CD4+ T-cell count Log10viral load Mean haematologic parameters ± SD
Variables Category N Mean ± SD [cell/μL] N Mean ± SD [copies/mL] N Hgb [g/dL] RBC [x106/mm3] WBC [x103/mm3] Platelet [x105/mm3]
ART duration (Months)          
 < 12 106 168.9 ± 143.8 118 3.60 ± 1.27 135 11.54 ± 2.09 3.58 ± 0.61 4.10 ± 1.49 2.50 ± 0.95
 12 – 36 255 266.3 ± 214.1§ 153 3.07 ± 1.38 294 11.97 ± 1.90 3.63 ± 0.59 4.33 ± 1.61 2.29 ± 0.77
 > 36 130 318.7 ± 220.5* 60 2.93 ± 1.05 192 12.56 ± 2.06 3.78 ± 0.66 4.69 ± 1.75δ 2.36 ± 0.77
p-value    < 0.001   0.001   < 0.001 0.008 0.004 0.054
Regimen type          
 EFV-based 163 241.0 ± 186.4 84 3.20 ± 1.37 179 11.91 ± 1.96 3.59 ± 0.59 4.28 ± 1.65 2.48 ± 0.97
 NVP-based 297 268.9 ± 219.8 243 3.26 ± 1.30 436 12.12 ± 2.06 3.69 ± 0.63 4.44 ± 1.65 2.31 ± 0.75
p-value    0.171   0.683   0.241 0.087 0.287 0.024
Co-Infection status          
 HIV only 398 274.3 ± 216.6 255 3.18 ± 1.35 574 12.14 ± 2.02 3.71 ± 0.62 4.44 ± 1.67 2.36 ± 0.76
 HIV/TB 66 171.1 ± 112.1 42 3.50 ± 1.34 63 10.89 ± 1.86 3.09 ± 0.42 3.89 ± 1.06 2.20 ± 1.22
p-value    < 0.001   0.166   < 0.001 < 0.001 0.011 0.154
  1. EFV-Efavirenz, NVP-Nevirapine, § higher than < 12 months [P = 0.03], * higher than < 12 months and 12–36 months [P < 0.001], lower than 12–36 and > 36 months [P < 0.02], lower than > 36 months [P = 0.02], higher than < 12 months [P = 0.012], δ higher 12 months [P = 0.004].