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Table 4 Demographic and socio-economic factors associated with virologic failure and risk estimates

From: Immuno-haematologic and virologic responses and predictors of virologic failure in HIV-1 infected adults on first-line antiretroviral therapy in Cameroon

Factors Demographic Virologic responses: prevalence, n (%) Risk estimates (95% CI)
  N VF AS p-value Crude odd ratio Adjusted odd ratio p-value
Gender:        
 Male 175 46 (26.3) 129 (73.7) 0.260 1.26 (0.84-1.87)   
 Female 502 111 (22.1) 391 (77.9)   1   
Age (years):        
 18 – 29 96 31 (32.3) 65 (67.7) 0.002 2.81 (1.55-5.10) 0.27 (0.10-0.83) 0.024
 30 – 45 402 100 (24.9) 302 (75.1)   1.95 (1.21-3.13) 0.44 (0.20-1.07) 0.079
 > 45 179 26 (14.5) 153 (85.5)   1 1  
Region:        
 Northwest 120 39 (32.5) 81 (67.5) 0.008 1.79 (1.16-2.76) 0.20 (0.10-0.74)*  
 Southwest 557 118 (21.2) 439 (78.8)   1 1  
Distance to TC:        
 Out of municipality 281 80 (28.5) 201 (71.5) < 0.001 2.30 (1.53-3.46) 0.42 (0.20-0.94) 0.011
 Within municipality 312 46 (14.7) 266 (85.3)   1 1  
Socio-economic        
Level of education        
 Low (≤ 7yrs. of school) 273 46 (16.8) 227 (83.2) 0.118 0.72 (0.47-1.09)   
 High (> 7 yrs. of school) 309 68 (22.0) 241 (78.0)   1   
Income level:        
 ≤ 50,000 XAF ɖ 480 94 (19.6) 386 (80.4) 0.960 0.99 (0.58-1.69)   
 > 50,000 XAF 101 20 (19.8) 81 (80.2)   1   
Marital status:        
 Never married 167 45 (25.7) 124 (74.3)   1.57 (0.92-2.69)   
 Currently married 245 42 (17.1) 203 (82.9) 0.079 0.94 (0.55-1.59)   
 Previously married 155 28 (18.1) 127 (81.9)   1   
  1. * Model including region of residence and excluding HIV/TB co-infection, VF: Virologic failure (viral load > 400 RNA copies/mL after 6 months of ART), AD: Adequate suppression (≤ 400 RNA copies/mL after 6 months of treatment), TC: treatment centre, CI- confidence interval, ɖ 50,000 XAF = ~ 100 US dollars.