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Table 3 Sensitivity of P. falciparum to piperaquine

From: Surveillance of antimalarial drug resistance in China in the 1980s–1990s

Province In vitro test In vivo test
Year No. of cases examined Resistance rate(%) Inhibition concentration(pmoll)* Year No. of cases examined Resistance rate(%) RIII(%)**
Hainan 1985 38 15.5 9.7 ± 9.1 1984 64 17.2 0
1997 70 72.9 47.9 ± 36.5 1997 42 50.0 71.4
Yunnan 1990 47 21.3 19.0 ± 17.2     
1993 37 73.0 38.0 ± 32.5     
  1. *The mean concentration of piperaquine for complete inhibition of schizont maturation.
  2. **Percentage of RIII cases in total resistant cases.