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Table 3 Sensitivity of P. falciparum to piperaquine

From: Surveillance of antimalarial drug resistance in China in the 1980s–1990s

Province

In vitro test

In vivo test

Year

No. of cases examined

Resistance rate(%)

Inhibition concentration(pmoll)*

Year

No. of cases examined

Resistance rate(%)

RIII(%)**

Hainan

1985

38

15.5

9.7 ± 9.1

1984

64

17.2

0

1997

70

72.9

47.9 ± 36.5

1997

42

50.0

71.4

Yunnan

1990

47

21.3

19.0 ± 17.2

    

1993

37

73.0

38.0 ± 32.5

    
  1. *The mean concentration of piperaquine for complete inhibition of schizont maturation.
  2. **Percentage of RIII cases in total resistant cases.