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Fig. 2 | Infectious Diseases of Poverty

Fig. 2

From: High-throughput screening against thioredoxin glutathione reductase identifies novel inhibitors with potential therapeutic value for schistosomiasis

Fig. 2

Primary HTS experiment. A collection of 59,360 compounds were screened using the optimized endpoint SmTGR fluorescence assay at an average final concentration of 10 μM for each compound. Sixteen positive (30 μM naphthazarin) and negative (DMSO) control reactions were plated to calculate % inhibition. Dashed line indicates 90 % inhibition of the initial threshold for hits

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