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Table 3 Clinical characteristics of study subjects at baseline, 2nd, 5th and 6th months of anti-TB treatment period, September 2013- March 2015

From: Diabetes mellitus is associated with increased mortality during tuberculosis treatment: a prospective cohort study among tuberculosis patients in South-Eastern Amahra Region, Ethiopia

Months of anti-TB therapy

Clinical symptoms

Baseline (n = 1314)a

2nd month (n = 1283)a

5th month (n = 1246)a

6th month (n = 1229)a

 

TBNDM

n (%)

TBDM

n (%)

P-value

TBNDM

n (%)

TBDM

n (%)

P-value

TBNDM

n (%)

TBDM

n (%)

P-value

TBNDM

n (%)

TBDM

n (%)

P-value

Cough

784 (65.1)

79 (72.5)

0.12

166 (14.0)

23 (23.0)

0.02

24 (2.1)

2 (2.2)

1.00*

18 (1.6)

2 (2.2)

0.66*

Fever

933 (78.4)

80 (73.4)

0.34

166 (14.0)

18 (18.0)

0.28

29 (2.5)

2 (2.2)

1.00*

13 (1.1)

1 (1.1)

1.00*

Hemoptysis

228 (18.9)

24 (22.0)

0.43

18 (1.5)

6 (6.0)

0.008

4 (0.3)

-

-

1 (0.1)

-

-

Weight loss

949 (78.8)

94 (86.2)

0.06

86 (7.3)

14 (14.0)

0.02

14 (1.2)

2 (2.2)

0.34*

10 (0.9)

1 (1.1)

0.58*

Poor appetite

922 (76.5)

86 (78.9)

0.57

154 (13.0)

16 (16.0)

0.39

25 (2.2)

2 (2.2)

1.00*

10 (0.9)

-

-

Night sweat

818 (67.9)

75 (68.8)

0.84

121 (10.2)

6 (6.0)

0.17

21 (1.8)

2 (2.2)

0.69*

14 (1.2)

2 (2.2)

0.34*

Dyspnea

587 (48.7)

52 (47.7)

0.84

93 (7.9)

9 (9.0)

0.68

24 (2.1)

2 (2.2)

1.00*

9 (0.8)

2 (2.2)

0.20*

Chest pain

683 (56.7)

64 (58.7)

0.68

108 (9.1)

9 (9.0)

0.96

26 (2.3)

4 (4.3)

0.27*

9 (0.8)

2 (2.2)

0.20*

Fatigue

967 (80.2)

90 (82.6)

0.56

207 (17.5)

29 (29.0)

0.004

46 (4.0)

5 (5.4)

0.42*

21 (1.8)

3 (3.2)

0.42*

BMI (kg/m2)

            

<18.5

720 (69.5)

59 (54.1)

 

567 (47.9)

48 (48.0)

 

424 (36.8)

37 (39.8)

 

377 (33.2)

33 (35.5)

 

18.5–24.9

445 (36.9)

44 (40.4)

 

583 (49.3)

42 (42.0)

 

686 (59.5)

48 (51.6)

 

713 (62.8)

51 (54.8)

 

≥25

31 (2.6)

6 (5.5)

0.13*

33 (2.8)

10 (10.0)

0.002*

42 (3.6)

8 (8.6)

0.05*

46 (4.0)

9 (9.7)

0.04*

Mean (± SD)

18.05 (±2.94)

18.35(±3.72)

0.31

18.95 (±5.79)

21.29 (±20.46)

0.005

19.55 (±3.50)

19.98 (±3.86)

0.26*

19.78 (±2.87)

20.58 (±4.95)

0.02

  1. TB: tuberculosis, TBNDM: TB without DM, TBDM: TB and DM, BMI: body mass index, kg: kilogram, m 2: meter square, SD: standared deviation
  2. *Fisher’s exact test
  3. athe number of total patients