Months of anti-TB therapy | ||||||||||||
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Clinical symptoms | Baseline (n = 1314)a | 2nd month (n = 1283)a | 5th month (n = 1246)a | 6th month (n = 1229)a | ||||||||
TBNDM n (%) | TBDM n (%) | P-value | TBNDM n (%) | TBDM n (%) | P-value | TBNDM n (%) | TBDM n (%) | P-value | TBNDM n (%) | TBDM n (%) | P-value | |
Cough | 784 (65.1) | 79 (72.5) | 0.12 | 166 (14.0) | 23 (23.0) | 0.02 | 24 (2.1) | 2 (2.2) | 1.00* | 18 (1.6) | 2 (2.2) | 0.66* |
Fever | 933 (78.4) | 80 (73.4) | 0.34 | 166 (14.0) | 18 (18.0) | 0.28 | 29 (2.5) | 2 (2.2) | 1.00* | 13 (1.1) | 1 (1.1) | 1.00* |
Hemoptysis | 228 (18.9) | 24 (22.0) | 0.43 | 18 (1.5) | 6 (6.0) | 0.008 | 4 (0.3) | - | - | 1 (0.1) | - | - |
Weight loss | 949 (78.8) | 94 (86.2) | 0.06 | 86 (7.3) | 14 (14.0) | 0.02 | 14 (1.2) | 2 (2.2) | 0.34* | 10 (0.9) | 1 (1.1) | 0.58* |
Poor appetite | 922 (76.5) | 86 (78.9) | 0.57 | 154 (13.0) | 16 (16.0) | 0.39 | 25 (2.2) | 2 (2.2) | 1.00* | 10 (0.9) | - | - |
Night sweat | 818 (67.9) | 75 (68.8) | 0.84 | 121 (10.2) | 6 (6.0) | 0.17 | 21 (1.8) | 2 (2.2) | 0.69* | 14 (1.2) | 2 (2.2) | 0.34* |
Dyspnea | 587 (48.7) | 52 (47.7) | 0.84 | 93 (7.9) | 9 (9.0) | 0.68 | 24 (2.1) | 2 (2.2) | 1.00* | 9 (0.8) | 2 (2.2) | 0.20* |
Chest pain | 683 (56.7) | 64 (58.7) | 0.68 | 108 (9.1) | 9 (9.0) | 0.96 | 26 (2.3) | 4 (4.3) | 0.27* | 9 (0.8) | 2 (2.2) | 0.20* |
Fatigue | 967 (80.2) | 90 (82.6) | 0.56 | 207 (17.5) | 29 (29.0) | 0.004 | 46 (4.0) | 5 (5.4) | 0.42* | 21 (1.8) | 3 (3.2) | 0.42* |
BMI (kg/m2) | ||||||||||||
<18.5 | 720 (69.5) | 59 (54.1) | 567 (47.9) | 48 (48.0) | 424 (36.8) | 37 (39.8) | 377 (33.2) | 33 (35.5) | ||||
18.5–24.9 | 445 (36.9) | 44 (40.4) | 583 (49.3) | 42 (42.0) | 686 (59.5) | 48 (51.6) | 713 (62.8) | 51 (54.8) | ||||
≥25 | 31 (2.6) | 6 (5.5) | 0.13* | 33 (2.8) | 10 (10.0) | 0.002* | 42 (3.6) | 8 (8.6) | 0.05* | 46 (4.0) | 9 (9.7) | 0.04* |
Mean (± SD) | 18.05 (±2.94) | 18.35(±3.72) | 0.31 | 18.95 (±5.79) | 21.29 (±20.46) | 0.005 | 19.55 (±3.50) | 19.98 (±3.86) | 0.26* | 19.78 (±2.87) | 20.58 (±4.95) | 0.02 |