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Table 2 Univariate analysis of association between influencing factors and treatment adherence (n = 481)

From: Are tuberculosis patients adherent to prescribed treatments in China? Results of a prospective cohort study

Variables Total n Adherent OR (95 % CI) P value
  Yes, n (%) No, n (%)   
Gender      
 Male 326 199 (61.0) 127 (39.0) 1.00  
 Female 155 109 (70.3) 46 (29.7) 0.66 (0.44-0.99) 0.047 f
Age (in years)      
 ≤18 43 23 (53.5) 20 (46.5) 1.00  
 19–49 297 199 (67.1) 98 (32.9) 0.57 (0.30-1.08) 0.820
 ≥50 141 86 (61.0) 55 (39.0) 0.74 (0.37-1.46) 0.381
Occupationa      
 Farmer 86 57 (66.3) 29 (33.7) 1.00  
 Employed worker 166 105 (63.3) 61 (36.8) 1.14 (0.66-1.97) 0.635
 Student 65 40 (61.5) 25 (38.5) 1.31 (0.67-2.56) 0.427
 Laid-off or unemployed 85 57 (67.1) 28 (32.9) 0.97 (0.51-1.82) 0.914
 Others 79 49 (62.0) 30 (38.0) 1.20 (0.64-2.28) 0.569
Educational level      
 Primary school or below 120 69 (57.5) 51 (42.5) 1.00  
 Junior middle school 154 102 (66.2) 52 (33.8) 0.69 (0.42-1.13) 0.139
 High school and above 207 137 (66.2) 70 (33.8) 0.69 (0.44-1.10) 0.127
Marital status      
 Married 360 230 (63.9) 130 (36.1) 1.00  
 Unmarried 106 67 (57.6) 39 (42.5) 1.03 (0.66-1.61) 0.898
 Divorced/loss of spouse 15 11 (73.3) 4 (26.7) 0.64 (0.20-2.06) 0.455
Annual per capita income (RMB)b      
 ≤9000 198 118 (59.6) 80 (40.4) 1.00  
 9000-18000 193 128 (66.3) 65 (33.7) 0.75 (0.50–1.13) 0.169
 ≥18000 78 51 (65.4) 27 (34.6) 0.78 (0.45–1.35) 0.374
Study site      
 CC 101 65 (64.4) 36 (35.6) 1.00  
 SS 185 128 (69.2) 57 (30.8) 0.79 (0.48–1.31) 0.146
 YY 195 115 (59.0) 80 (41.0) 1.26 (0.76–2.07) 0.369
Residence statusc      
 Local residents 422 275 (65.2) 147 (34.8) 1.00  
 Migrant workers 59 33 (55.9) 26 (44.1) 1.47 (0.85–2.56) 0.106
Time spending to TB care institution      
 ≤ One hour 284 191 (67.3) 93 (32.8) 1.00  
 > One hour 197 117 (59.4) 80 (40.6) 1.43(0.98–2.09) 0.060
Health insurance      
 Yes 387 241 (62.3) 146 (37.7) 1.00  
 No 94 67 (71.3) 27 (28.7) 0.67 (0.41–1.09) 0.103
Pulmonary TB type      
 Smear-positive 156 105 (67.3) 51 (32.7) 1.00  
 Smear-negative 325 203 (62.5) 122 (37.5) 1.24 (0.83–1.85) 0.300
TB-related education by physicians      
 Yes 280 188 (67.1) 92 (32.9) 1.00  
 No 201 120 (62.7) 81 (37.3) 1.38 (0.952.01) 0.093
Treatment observation      
 Self-administrated 414 278 (67.2) 136 (32.9) 1.00  
 Family members 55 18 (32.7) 37 (67.3) 4.20 (2.31–7.65) <0.001
 Primary health workers 12 11 (91.7) 1 (8.3) 0.67 (0.63–0.72) <0.001
Regular supervision contact      
 No supervision contact 152 67 (44.1) 85 (55.9) 1.00  
 Home visit 38 36 (94.7) 2 (5.3) 0.44 (0.01–0.19) <0.001
 Telephone call 291 205 (70.5) 86 (29.6) 0.33 (0.22–0.50) <0.001
Adverse effectsd      
 Yes 123 80 (65.0) 43 (35.0) 1.00  
 No 358 228 (63.7) 130 (36.3) 1.06 (0.69–1.63) 0.787
Monthly treatment coste (CNY)      
 ≤450 246 172 (69.9) 74 (30.1) 1.00  
 >450 235 136 (57.9) 99 (42.1) 1.69 (1.16–2.46) 0.006
  1. aIn the occupation category, employed workers include factory worker, building worker, food service staff, driver, administrative sector staff and teacher; others include individual peddler, freelance and retired staff
  2. bAnnual per capita income refers to ‘Chongqing Statistic Yearbook’ [Chongqing statistical yearbook (in Chinese). Chongqing: China Statistics Bureau Press; 2013], the annual income levels of urban and rural areas were categorized into middle-income (CNY 18000) and low-income (CNY 9000). A total of 12 patients did not fill in this blank
  3. cLocal residents in our study mean the patients have lived and worked in the study sites for at least 12 months; migrant workers refer to the patients temporarily living in the study sites and receiving treatment but may move along with floating work at any time
  4. dAdverse effects include nausea or vomiting, hands or feet numbness, dizziness, headaches, insomnia, skin rash, etc
  5. eTreatment cost include direct expenditure on self-paid TB drugs, liver protecting drugs, cough remission drugs, traveling, accommodation and nourishment. 450 RMB is the median cost
  6. fVariables with a P-value less than or close to 0.10 in the univariate analysis were included in the multivariate logistic regression analysis