| |
ALL (250)
|
Artesunate-amodiaquine (120)
|
Artemether-lumefantrine (130)
|
P value
|
|---|
|
Parasite prevalence on day 1
|
126
|
58
|
68
|
0.62
|
|
Parasite positivity rate on day 3
|
3
|
2
|
1
|
0.61
|
|
PRRD1
|
|
Geometric mean
|
5.5 × 102
|
5.6 × 102
|
5.4 × 102
|
0.79
|
|
Range
|
1.1 × 10−1–2.9 × 105
|
1.1 × 10−1–1.3 × 105
|
4.1 × 10−1–2.9 × 105
|
|
PRRD2
|
|
Geometric mean
|
1.1 × 104
|
1.0 × 104
|
1.1 × 104
|
0.7
|
|
Range
|
1.9 × 101–3.0 × 105
|
1.9 × 101–1.3 × 105
|
2.6 × 101–3.0 × 105
|
|
Fever clearance time (day)
|
|
Mean
|
1.3
|
1.3
|
1.4
|
0.83
|
|
95 % CI
|
1.2–1.5
|
1.1–1.5
|
1.1–1.6
|
|
Parasite clearance time (day)
|
|
Mean
|
1.6
|
1.5
|
1.6
|
0.46
|
|
95 % CI
|
1.5–1.7
|
1.4–1.7
|
1.5–1.7
|
-
PRR
D1
parasite reduction ratio 1 day after treatment started, PRR
D2
parasite reduction ratio 2 days after treatment started, ALL all children
