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Table 4 Other measures of treatment outcomes in children ≤ 2 treated with artesunate-amodiaquine or artemether-lumefantrine

From: Therapeutic efficacy and effects of artesunate-amodiaquine and artemether-lumefantrine on malaria-associated anaemia in Nigerian children aged two years and under

  ALL (250) Artesunate-amodiaquine (120) Artemether-lumefantrine (130) P value
Parasite prevalence on day 1 126 58 68 0.62
Parasite positivity rate on day 3 3 2 1 0.61
PRRD1
 Geometric mean 5.5 × 102 5.6 × 102 5.4 × 102 0.79
 Range 1.1 × 10−1–2.9 × 105 1.1 × 10−1–1.3 × 105 4.1 × 10−1–2.9 × 105
PRRD2
 Geometric mean 1.1 × 104 1.0 × 104 1.1 × 104 0.7
 Range 1.9 × 101–3.0 × 105 1.9 × 101–1.3 × 105 2.6 × 101–3.0 × 105
Fever clearance time (day)
 Mean 1.3 1.3 1.4 0.83
 95 % CI 1.2–1.5 1.1–1.5 1.1–1.6
Parasite clearance time (day)
 Mean 1.6 1.5 1.6 0.46
 95 % CI 1.5–1.7 1.4–1.7 1.5–1.7
  1. PRR D1 parasite reduction ratio 1 day after treatment started, PRR D2 parasite reduction ratio 2 days after treatment started, ALL all children