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Table 4 Other measures of treatment outcomes in children ≤ 2 treated with artesunate-amodiaquine or artemether-lumefantrine

From: Therapeutic efficacy and effects of artesunate-amodiaquine and artemether-lumefantrine on malaria-associated anaemia in Nigerian children aged two years and under

 

ALL (250)

Artesunate-amodiaquine (120)

Artemether-lumefantrine (130)

P value

Parasite prevalence on day 1

126

58

68

0.62

Parasite positivity rate on day 3

3

2

1

0.61

PRRD1

 Geometric mean

5.5 × 102

5.6 × 102

5.4 × 102

0.79

 Range

1.1 × 10−1–2.9 × 105

1.1 × 10−1–1.3 × 105

4.1 × 10−1–2.9 × 105

PRRD2

 Geometric mean

1.1 × 104

1.0 × 104

1.1 × 104

0.7

 Range

1.9 × 101–3.0 × 105

1.9 × 101–1.3 × 105

2.6 × 101–3.0 × 105

Fever clearance time (day)

 Mean

1.3

1.3

1.4

0.83

 95 % CI

1.2–1.5

1.1–1.5

1.1–1.6

Parasite clearance time (day)

 Mean

1.6

1.5

1.6

0.46

 95 % CI

1.5–1.7

1.4–1.7

1.5–1.7

  1. PRR D1 parasite reduction ratio 1 day after treatment started, PRR D2 parasite reduction ratio 2 days after treatment started, ALL all children