World Health Organisation operational diagnostic criteria for leprosy
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1. Skin lesion consistent with leprosy and with definite sensory loss, with or without thickened nerves
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2. Positive skin smears
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In an endemic country or area, an individual should be regarded as having leprosy if he or she shown ONE of the above cardinal signs. Only in rare instances is there a need to use laboratory and other investigations to confirm a diagnosis. Adapted from WHO [5]