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Table 1 Clinical data and A2ML1 duplication variant genotypes of indigenous Filipinos with ear swabs

From: Middle ear microbiome differences in indigenous Filipinos with chronic otitis media due to a duplication in the A2ML1 gene

ID

Age (yrs)

Sex

GT

Side

Otoscopic findings

2

10

F

wt

L

20 % perforation and copious yellowish foul-smelling discharge; reddish dull TM

5

10

M

het

B

60-80 % perforation with purulent foul-smelling discharge

7

4

M

het

R

30 % perforation with purulent thick non-foul-smelling discharge

8

24

F

wt

L

20 % perforation, dry

20

6

F

het

R

20 % perforation, scanty non-foul-smelling discharge

33

9

M

wt

B

near-total perforation with thick purulent non-foul-smelling discharge

41

10

F

het

R

70 % perforation with moist middle ear mucosa

45

19

F

het

B a

B: 20 % perforation with yellowish non-foul-smelling discharge: L: granulation tissue

53

14

F

het

B

30-40 % perforation with discharge

62

6

M

hom

R

20 % perforation with non-foul-smelling discharge

63

13

F

hom

B

40-90 % perforation with moist middle ear mucosa

67

6

F

het

L

20 % perforation, dry

71

12

F

wt

L

50 % perforation with moist middle ear mucosa

76

7

M

wt

B b

L: 30 % perforation with discharge; R: intact but retracted TM

89

4

F

het

B b

R: foul-smelling discharge; L: dull, bulging erythematous TM

92

7

M

het

B

filled with granulation tissue and foul-smelling discharge

  1. GT genotype, F female, M male, wt wildtype, het heterozygous, hom homozygous, L left, R right, B bilateral, TM tympanic membrane
  2. aID 45 has chronic otitis media bilaterally but middle ear sample is available only for the right ear
  3. bPerforation only in one ear, for which a middle ear sample was obtained