|Disease||Agent||Vector||Burden||Existing prevention strategies||Challenges for VBD control|
|Malaria||Parasite (Plasmodiu, five species)||Anopheles (more than 60 species)||Transmission in 97 countries. About 3.4 billion people at risk.||
Outdoor and indoor residual spraying|
Bed nets (traditional and long lasting insecticidal nets)
Environmental management: Reducing breeding sites by managing water storage, draining water recipients, cleaning backyards, and waste management
Biological control: Introduction of parasites or predators to control de vectors.
Genetic control: Use of Wolbachia
Chemoprophylaxis: Prophylaxis and preventive therapies, mass treatment, vaccines
Lack of expertise in vector control|
Limited sanitation and limited access to safe drinking water
Resistance to insecticides
Limited research on fidelity of implemented measures
Lack of intersectoral work
|Dengue||Virus (Flavivirus = Dengue virus, 4 serotypes)||Aedes Aegypti (same vector for yellow fever, Chicungunya and Zika virus)||
More than 100 countries at risk.|
2.5 billion people at risk.
|Leishmaniasis Cutaneus (CL); Mucocutaneous (MCL) and Visceral (VL).||Parasites-Protozoa (Leishmania sp, more than 20 species)||Sand flies (Lutzomya)||
1.3 million new cases every year.|
More than 65 % of CL occurs in six countries. MCL occurs mainly in three countries of the Americas.
|American Trypanosomiasis, Chagas||Parasite (Trypansosoma cruzi)||Triatomine bugs||10 million infected people worldwide.|
|Human African Trypanosomiasis (sleeping sickness)||Parasite (Trypanosoma brucei gambiense)||Flies (tsetse fly)||Occurs in 36 sub-Saharan Africa countries. Yearly cases are under 20 000 and 65 are estimated to be at risk.|
|Lyme disease||Bacteria (Borrelia)||Ticks (Ixodes Ticks)||7.9 cases per 100 000 people in the US. Occurs in Asia, Europe and North America.|