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Table 3 Multiple cox regression predictors of mortality among Tb/HIV patients at JUTH, Southwest Ethiopia, 2013

From: Predictors of mortality in a cohort of tuberculosis/HIV co-infected patients in Southwest Ethiopia

Variable

Tb/HIV Co-infection Status (n = 272)

Crude Hazard Ratio (95%CI)

Adjusted Hazard Ratio (95 % CI)

 

Alive, n (%)

Died, n (%)

  

Age in years

 15–24

32 (14.7) 114

6 (10.9)

1

1

 25–34

(52.5) 48

26 (47.3) 21

1.1 (0.5–2.8)

1.4 (0.6–3.8)

 35–44

(22.1)

(38.2)

2.2 (0.9–5.4)*

2.9 (1.08–7.6)*

  > =45

23 (10.7)

2 (3.6)

0.6 (0.1–2.7)

0.3 (0.05–1.6)

Sex

 Male

91 (41.9)

23 (41.8)

1

1

 Female

126 (58.1)

32 (58.2)

1.1 (0.7–1.9)

1.7 (0.8–3.5)

Educational status

 Illiterate

61 (28.1)

20 (36.4)

1

1

 Read and write

39 (18)

12 (21.8)

0.7 (0.3–1.3)

0.9 (0.3–2.4)

 Formal education

117 (53.9)

23 (41.8)

0.4 (0.2–0.7)*

0.6 (0.2–1.8)

Occupation

 Gov’t employed

40 (18.4)

8 (14.5)

1

1

 NGO

37 (17.1)

9 (16.4)

1.1 (0.4–2.9)

0.9 (0.4–2.6)

 Farmer

69 (31.8)

11 (20)

1.06 (0.4–2.6)

0.7 (0.3–1.9)

 Daily labour

64 (29.5)

22 (40)

2.4 (1.04–5.3)*

2.1 (0.9–4.9)

 CSW

7 (3.2)

5 (9.1)

6.7 (2.2–20.9)*

9.1 (2.7–30.7)*

Disclosure

 Yes

139 (64.1)

37 (67.3)

1

1

 No

78 (35.9)

18 (32.7)

0.7 (0.4–1.1)

0.7 (0.3–1.8)

Function

 Work

112 (51.6)

26 (47.3)

1

1

 Ambulatory

79 (36.4)

16 (29.1)

0.6 (0.3–1.09)

1.05 (0.5–2.1)

 Bed ridden

26 (12)

13 (23.6)

0.5 (0.2–1.05)

3.2 (1.2–8.7)*

WHO stage

 1

11 (5.1)

7 (12.7)

1

1

 2

55 (25.3)

12 (21.8)

0.3 (0.1–0.9)*

0.2 (0.06–0.5)*

 3

101 (46.5)

23 (41.8)

0.4 (0.2–1.02)

0.3 (0.1–0.8)*

 4

50 (23.1)

13 (23.7)

0.4 (0.2–1.09)

0.2 (0.04–0.5)*

Tb type

 Pulmonary

172 (79.3)

41 (74.5)

1

1

 Extra-pulmonary

11 (5.1)

3 (5.5)

0.6(0.3–1.07)

2.6(0.5–12.2)

 Mixed

34 (15.6)

11 (20)

1(0.3–3.6)

0.9(0.3–2.7)

Risky behaviour

 Yes

153 (70.5)

38 (69.1)

1

1

 No

64 (29.5)

17 (30.9)

0.9 (0.5–1.6)

0.8 (0.4–1.9)

Partner HIV status

 Positive

150 (69.1)

39 (70.9)

1

1

 Negative/Unknown

67 (30.9)

16 (29.1)

1.4 (0.8–2.5)

0.5 (0.2–1.5)

  1. *Statistically significant at P < 0.05