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Table 6 Leprosy reactions among patients enrolled at UMDT/CT-BR according to treatment group

From: Can baseline ML Flow test results predict leprosy reactions? An investigation in a cohort of patients enrolled in the uniform multidrug therapy clinical trial for leprosy patients in Brazil

  PB UMDT
N (%)
PB RMDT
N (%)
MB UMDT
N (%)
MB RMDT
N (%)
Total
N (%)
Reactions 17 (22.1) 12 (14.6) 214 (66.7) 175 (64.1) 418 (55.5)
RR 6 (7.8) 4 (4.9) 69 (21.5) 59 (21.6) 138 (18.3)
ENL 0 0 20 (6.2) 21 (7.7) 41 (5.4)
RR + Neu 1 (1.3) 2 (2.4) 15 (4.7) 10 (3.7) 28 (3.7)
ENL + Neu 0 0 5 (1.6) 2 (0.7) 7 (0.9)
Neuritis 10 (13) 6 (7.3) 79 (24.6) 54 (19.8) 149 (19.8)
Others 0 0 26 (8.1) 29 (10.6) 55 (7.3)
Reaction-free 60 (77.9) 70 (85.4) 107 (33.3) 98 (35.9) 335 (44.5)
Total 77 (100) 82 (100) 321 (100) 273 (100) 753 (100)
  1. For the statistical analysis of PB patients were excluded ENL and ENL + neuritis. RR and RR + neuritis were grouped
  2. RR Reversal reaction, ENL Eritema Nodosum Leprosum, Neu neuritis, Others others manifestations
  3. PB – x 2 (2) = 1.69; p = 0.43; MB – x 2 (6) = 0.61; p = 0.61