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Table 4 Demographic, serological, and virological characteristics according to the clinical classifications of the 90 HBsAg-positive subjects with a conclusive clinical diagnosis

From: Hepatitis B virus infection in undocumented immigrants and refugees in Southern Italy: demographic, virological, and clinical features

 

HBsAg pos. non-viremic asymptomatic carriers

HBsAg pos. viremic asymptomatic carriers

HBsAg pos. patients with chronic hepatitis

HBsAg-pos. patients with cirrhosis

N° of patients

29

43

14

4

Age, years, median (range)

32 (22–58)

32.5 (20–55)

32.5 (18–44)

32.5 (25–35)

Males, n° (%)

25 (86)

35 (83.3)

14

4

Status in country, n° (% by row)

 Undocumented immigrants, 63 cases

14 (22.2)

32 (50.8)

13 (20.6)

4 (6.4)

 Low-income refugees, 27 cases

15 (52)

11 (26.2)

1 (7)

0

In Italy for month, mean ± SD

35.7 ± 32.7

42 ± 58.6

49.4 ± 28.8

50 ± 52.3

Years of schooling, mean ± SD

3.5 ± 4.2

2.5 ± 4

11.9 ± 19.8

2.7 ± 3.8

Country of origin, n° (% by row)

    

 Eastern Europe, 10 cases

1 (10.0)

5 (50.0)

4 (40.0)

0

 North Africa, 1 case

0

1 (100)

0

0

 SSA, 75 cases

27 (36)

35 (46.7)

10 (13.3)

3 (4)

 Asia, 4 cases

1 (25)

2 (50)

0

1 (25)

 America, no cases

0

0

0

0

Anti-delta-positive, n°(% by column)

0

1 (2.4)

1 (7)

0

HBeAg positive/anti-HBe negative, n° (% by column)

0

0

4 (28.6)

2 (50)

HBeAg negative/anti-HBe positive, n° (% by column)

29 (100)

43 (100)

10 (71.4)

2 (50)

HBV DNA, IU/ml, median (range)

--

620 (12–73 000)

8,500

(2.4E3–1.0E9)

1.2E7

(1.3E–1.7E8)

AST, IU/ml, mean ± SD

18 ± 3.7

23.6 ± 7.2

72.7 ± 82.5

41 ± 22

ALT, IU/ml, mean ± SD

19 ± 4.3

24.7 ± 7

98.5 ± 117.8

53 ± 32.2

HBV genotype, n° (% by row)

 A

//

8 (72.7)

2 (18.2)

1 (9.1)

 C

 

0

0

1 (25)

 D

 

4 (57.1)

3 (42.9)

0

 E

 

18 (64.3)

8 (28.6)

2 (7.1)

Not determined

 

13 (92.9)

1 (7.1)

0

  1. AST aspartate-aminotransferases, ALT alanine-aminotransferase