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Table 4 Demographic, serological, and virological characteristics according to the clinical classifications of the 90 HBsAg-positive subjects with a conclusive clinical diagnosis

From: Hepatitis B virus infection in undocumented immigrants and refugees in Southern Italy: demographic, virological, and clinical features

  HBsAg pos. non-viremic asymptomatic carriers HBsAg pos. viremic asymptomatic carriers HBsAg pos. patients with chronic hepatitis HBsAg-pos. patients with cirrhosis
N° of patients 29 43 14 4
Age, years, median (range) 32 (22–58) 32.5 (20–55) 32.5 (18–44) 32.5 (25–35)
Males, n° (%) 25 (86) 35 (83.3) 14 4
Status in country, n° (% by row)
 Undocumented immigrants, 63 cases 14 (22.2) 32 (50.8) 13 (20.6) 4 (6.4)
 Low-income refugees, 27 cases 15 (52) 11 (26.2) 1 (7) 0
In Italy for month, mean ± SD 35.7 ± 32.7 42 ± 58.6 49.4 ± 28.8 50 ± 52.3
Years of schooling, mean ± SD 3.5 ± 4.2 2.5 ± 4 11.9 ± 19.8 2.7 ± 3.8
Country of origin, n° (% by row)     
 Eastern Europe, 10 cases 1 (10.0) 5 (50.0) 4 (40.0) 0
 North Africa, 1 case 0 1 (100) 0 0
 SSA, 75 cases 27 (36) 35 (46.7) 10 (13.3) 3 (4)
 Asia, 4 cases 1 (25) 2 (50) 0 1 (25)
 America, no cases 0 0 0 0
Anti-delta-positive, n°(% by column) 0 1 (2.4) 1 (7) 0
HBeAg positive/anti-HBe negative, n° (% by column) 0 0 4 (28.6) 2 (50)
HBeAg negative/anti-HBe positive, n° (% by column) 29 (100) 43 (100) 10 (71.4) 2 (50)
HBV DNA, IU/ml, median (range) -- 620 (12–73 000) 8,500 (2.4E3–1.0E9) 1.2E7 (1.3E–1.7E8)
AST, IU/ml, mean ± SD 18 ± 3.7 23.6 ± 7.2 72.7 ± 82.5 41 ± 22
ALT, IU/ml, mean ± SD 19 ± 4.3 24.7 ± 7 98.5 ± 117.8 53 ± 32.2
HBV genotype, n° (% by row)
 A // 8 (72.7) 2 (18.2) 1 (9.1)
 C   0 0 1 (25)
 D   4 (57.1) 3 (42.9) 0
 E   18 (64.3) 8 (28.6) 2 (7.1)
Not determined   13 (92.9) 1 (7.1) 0
  1. AST aspartate-aminotransferases, ALT alanine-aminotransferase