Table 6 Comparison of key amino acid residues of the E protein related to neurovirulence of JEVa
Strain | E107 | E138 | E176 | E177 | E264 | E279 | E315 | E439 |
|---|---|---|---|---|---|---|---|---|
SA-14-14-2 (GIII) | Phe(F) | Lys(K) | Val(V) | Ala(A) | His(H) | Met(M) | Val(V) | Arg(R) |
SXYC1523b(GI) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |
SXYC1546b(GI) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |
SXYC1548b(GI) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |
SX09S-01(GI) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |
12-YJ033(GI) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |
GZ56(GI) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |
FU(GII) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |
Nakayama(GIII) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |
P3 (GIII) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |
JKT6468(GIV) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |
Muar(GV) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |
XZ0934(GV) | Leu(L) | Glu(E) | Ile(I) | Thr(T) | Gln(Q) | Lys(K) | Ala(A) | Lys(K) |