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Fig. 1 | Infectious Diseases of Poverty

Fig. 1

From: Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study

Fig. 1

Experimental design for longitudinal selection of Schistosoma mansoni under in vivo praziquantel pressure (0, 25, or 50 mg/kg) for three parasite lines (susceptible (S), resistant (R), and a coinfected line (RS)). Praziquantel treatment was administered to the mice 42 days after parasite exposure. Mice were culled between days 47 and 62. Resultant miracidia were used to infect the snail at 6 miracidia/snail. In P1 mice were infected with 220 cercariae/mouse. For F1-F3, 110 cercariae/mouse were used. The experimental design shown here is an example showing only the parasite line started with the S isolate

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