Fig. 1From: Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection studyExperimental design for longitudinal selection of Schistosoma mansoni under in vivo praziquantel pressure (0, 25, or 50Â mg/kg) for three parasite lines (susceptible (S), resistant (R), and a coinfected line (RS)). Praziquantel treatment was administered to the mice 42Â days after parasite exposure. Mice were culled between days 47 and 62. Resultant miracidia were used to infect the snail at 6 miracidia/snail. In P1 mice were infected with 220 cercariae/mouse. For F1-F3, 110 cercariae/mouse were used. The experimental design shown here is an example showing only the parasite line started with the S isolateBack to article page