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Table 5 Multinomial analysis adjusted by age and sex of the association between antibody response pattern, serotype and severity of dengue disease as outcome

From: Dengue-specific serotype related to clinical severity during the 2012/2013 epidemic in centre of Brazil

Parameters

Dengue with Warning Signs

Severe Dengue

OR Adj (95% CI)

P-value

OR Adj (95% CI)

P-value

Comorbidity

1.20 (0.72–2.00)

0.479

1.74 (0.64–4.73)

0.279

Antibody response pattern

 Primary

Reference

Reference

 Secondary

1.20 (0.76–1.89)

0.433

2.80 (0.78–10.0)

0.113

 Missing

1.93 (0.92–4.09)

0.083

6.23 (1.32–29.4)

0.021

Serotypea

 DENV-1

Reference

NA

 DENV-4

0.80 (0.45–1.41)

0.444

NA

 Not evaluated

0.95 (0.56–1.62)

0.856

NA

  1. aSerotypes determined by reverse-transcription polymerase chain reaction (RT-PCR)