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Table 2 Most prevalent drug resistant mutations in P. falciparum isolates from the slope of mount Cameroon

From: Molecular markers for artemisinin and partner drug resistance in natural Plasmodium falciparum populations following increased insecticide treated net coverage along the slope of mount Cameroon: cross-sectional study

Gene Codons This study Prevalence (isolates) Previous reports in areaα or elsewhere in Cameroonβ
Prevalence (isolates) Year of sampling Reference
Pfcrt M74I 55.0 (116) NR NR NR
N75E 54.2 (115) NR NR NR
K76 T(R,I) 55.2 (116) 87.1 2004–2006 Mbacham et al., 2010α [44]
Q271K 62.5 (120) NR NR NR
I356K 46.1 (77) NR NR NR
Pfdhfr N51I 99.6 (232) 96.1 (51) 2010–2011 Chauvin et al., 2015β [63]
C59R 99.6 (232) 98 (51)
S108 N 100 (233) 98 (51)
Pfdhps K142 N 9.2 (19) NR NR NR
I431V 17.6 (31) 9.8 (51) 2010–2011 Chauvin et al., 2015β [63]
S436A 32.0 (39) 47.1 (51)
A581G 9.8 (19) 5.9 (51)
A613S 12.3 (18) 11.8 (51)
Pfmdr1 N86Y 13.0 (25) 73.8 2004–2006 Mbacham et al., 2010α [44]
Y184F 72.0 (121) 9 (64) 1997–2000 Basco et al., 2002β [41]
Pfkelch13 K189 T 36.0 (58) NR NR NR
  1. α and β denote reports from the study area and elsewhere in Cameroon respectively; NR = No Reports