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Table 3 Sensitivity analysis on the impact of the number of visits at the treatment centre on average cost per patient and on the impact of productivity loss on average cost per patient

From: Health economic evaluation of moist wound care in chronic cutaneous leishmaniasis ulcers in Afghanistan

  Av. days open CL ulcer Av. cost per patient Av. direct non-medical cost per patient NMB (WTP = 1.92) INMB (WTP = 1.92)
% of av. cost Abs. value Group II: 6 visits Group II: 12 visits Group III: 6 visits Group III: 12 visits
Group I
 6 visits at treatment centre 174 10.13 27 2.71 238 90 86 29 25
 9 visits at treatment centre 174 11.43 36 4.07 236 92 88 31 27
 12 visits at treatment centre 174 12.50 43 5.42 235 93 89 32 28
Group IIa
 6 visits at treatment centre 126 11.82 35 4.09 328 0 −4 −61 −65
 9 visits at treatment centre 126 13.87 44 6.14 326 2 −2 −59 −63
 12 visits at treatment centre 126 15.91 51 8.18 324 4 0 −57 −61
 23 visits at treatment centre 126 23.42 67 15.69 316 12 8 − 49 −53
Group IIIa
 6 visits at treatment centre 156 14.88 24 3.56 267 61 57 0 −4
 9 visits at treatment centre 156 16.66 32 5.34 265 63 59 2 −2
 12 visits at treatment centre 156 18.44 39 7.12 263 65 61 4 0
 23 visits at treatment centre 156 24.97 55 13.65 257 71 67 10 6
  Av. days open CL ulcer Av. cost per patient Av. indirect cost per patient NMB (WTP = 1.92) INMB (WTP = 1.92)
% of av. cost Abs. value Group I: 1% prod. Loss Group I: 10% prod. Loss Group I: 20% prod. Loss
Group I
 1% productivity loss 174 11.43 28.96 3.31 236 30 63
 10% productivity loss 174 41.19 80.38 33.11 207 −30 −33
 20% productivity loss 174 74.26 89.17 66.22 174 −63 −33
Group II
 1% productivity loss 126 15.91 14.59 2.32 324 88 118 151
 10% productivity loss 126 36.60 62.79 22.98 304 67 97 130
 20% productivity loss 126 59.58 77.16 45.97 281 44 74 107
Group III
 1% productivity loss 156 24.97 11.62 2.90 257 20 50 83
 10% productivity loss 156 51.10 57.73 29.50 231 −6 24 57
 20% productivity loss 156 80.12 72.50 58.09 202 −35 −5 28
  1. a No changes have been made to the treatment protocol in each regimen, only the number of visits to the centre have been varied. Dressing changes can be done by the patient himself, visits at the centre can be reduced to a minimum check of the wound healing process. In Group I, 6 visits correspond to the WHO protocol, 6 visits to the average of visits including non-compliant patients, and 12 visits to the foreseen RCT protocol for IL SSG injections