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Table 5 Univariate and multivariate analysis of factors associated with BALF positivity in pulmonary TB sputum-negative suspects and those without sputum

From: Indicators for prediction of Mycobacterium tuberculosis positivity detected with bronchoalveolar lavage fluid

  Total BALF (+) BALF (−) P-value OR (95% CI)a
n = 285 (%) n = 743 (%)
Age (year)     < 0.001  
  ≤ 25 244 105 (43.0) 139 (57.0)   Reference
 25–35 288 88 (30.6) 200 (69.4)   0.582 (0.408–0.832)
 35–45 215 44 (20.5) 171 (79.5)   0.341 (0.224–0.517)
 45–55 128 22 (17.2) 116 (82.8)   0.251 (0.149–0.423)
 55–65 106 23 (21.7) 83 (78.3)   0.367 (0.217–0.621)
 > 65 37 3 (8.1) 34 (91.9)   0.117 (0.035–0.391)
Cavity     < 0.001  
 No 924 228 (24.7) 696 (75.3)   Reference
 Yes 104 57 (54.8) 47 (45.2)   4.108 (2.376–7.102)
IGRA     < 0.001  
 Negative 431 64 (14.8) 367 (85.2)   Reference
 Positive 507 201 (39.6) 306 (60.4)   3.743 (2.478–5.655)
CD8+     0.002  
 > 500 205 46 (22.5) 159 (77.5)   Reference
  ≤ 500 468 153 (32.7) 315 (67.3)   1.992 (1.289–3.076)
  1. TB tuberculosis, BALF bronchoalveolar lavage fluid, NAAT nucleic acid amplification test, IGRA interferon-γ release assays
  2. aControlling for variables with P < 0.05 in univariate analysis