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Table 5 Univariate and multivariate analysis of factors associated with BALF positivity in pulmonary TB sputum-negative suspects and those without sputum

From: Indicators for prediction of Mycobacterium tuberculosis positivity detected with bronchoalveolar lavage fluid

 

Total

BALF (+)

BALF (−)

P-value

OR (95% CI)a

n = 285 (%)

n = 743 (%)

Age (year)

   

< 0.001

 

  ≤ 25

244

105 (43.0)

139 (57.0)

 

Reference

 25–35

288

88 (30.6)

200 (69.4)

 

0.582 (0.408–0.832)

 35–45

215

44 (20.5)

171 (79.5)

 

0.341 (0.224–0.517)

 45–55

128

22 (17.2)

116 (82.8)

 

0.251 (0.149–0.423)

 55–65

106

23 (21.7)

83 (78.3)

 

0.367 (0.217–0.621)

 > 65

37

3 (8.1)

34 (91.9)

 

0.117 (0.035–0.391)

Cavity

   

< 0.001

 

 No

924

228 (24.7)

696 (75.3)

 

Reference

 Yes

104

57 (54.8)

47 (45.2)

 

4.108 (2.376–7.102)

IGRA

   

< 0.001

 

 Negative

431

64 (14.8)

367 (85.2)

 

Reference

 Positive

507

201 (39.6)

306 (60.4)

 

3.743 (2.478–5.655)

CD8+

   

0.002

 

 > 500

205

46 (22.5)

159 (77.5)

 

Reference

  ≤ 500

468

153 (32.7)

315 (67.3)

 

1.992 (1.289–3.076)

  1. TB tuberculosis, BALF bronchoalveolar lavage fluid, NAAT nucleic acid amplification test, IGRA interferon-γ release assays
  2. aControlling for variables with P < 0.05 in univariate analysis