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Table 6 Stratified analysis of factors associated with BALF positivity in pulmonary TB sputum-negative suspects and those without sputum

From: Indicators for prediction of Mycobacterium tuberculosis positivity detected with bronchoalveolar lavage fluid

  BALF (+) n/N (%) BALF (−) n/N (%) P-value OR (95% CI)
IGRA/Age    <0.001  
 IGRA (−)/> 35 year 30/239 (12.6) 209/239 (87.4)   Reference
 IGRA (−)/≤ 35 year 34/192 (17.7) 158/192 (82.3)   1.499 (0.880–2.554)
 IGRA (+)/> 35 year 55/212 (25.9) 157/212 (74.1)   2.441 (1.494–3.986)
 IGRA(+)/≤ 35 year 146/295 (49.5) 149/295 (50.5)   6.826 (4.372–10.658)
Cavity/Age    <0.001  
 Cavity (−)/> 35 year 76/453 (17.0) 371/477 (83.0)   Reference
 Cavity (−)/≤ 35 year 152/477 (31.9) 325/477 (68.1)   2.283 (1.669–3.122)
 Cavity (+)/> 35 year 16/49 (32.7) 33/49 (67.3)   2.367 (1.240–4.516)
 Cavity (+)/≤ 35 year 41/55 (74.5) 14/55 (25.5)   14.296 (7.426–27.521)
CD8/Age    <0.001  
 CD8> 500/> 35 year 16/82 (19.5) 66/82 (80.5)   Reference
 CD8> 500/≤ 35 year 30/117 (25.6) 87/117 (74.4)   1.422 (0.716–2.824)
 CD8 ≤ 500/> 35 year 49/222 (22.1) 173/222 (77.9)   1.168 (0.621–2.197)
 CD8 ≤ 500/ ≤ 35 year 104/246 (42.3) 142/246 (57.7)   3.021 (1.655–5.515)
IGRA/Cavity/Age    <0.001  
 IGRA (−)/Cavity (−)/> 35 year 24/219 (11.0) 195/219 (89.0)   Reference
 IGRA (−)/Cavity (−)/≤ 35 year 23/174 (13.2) 151/174 (86.8)   1.238 (0.672–2.278)
 IGRA (−)/Cavity (+)/> 35 year 6/20 (30.0) 14/20 (70.0)   3.482 (1.223–9.912)
 IGRA (−)/Cavity (+)/≤ 35 year 11/18 (61.1) 7/18 (38.9)   12.768 (4.521–36.056)
 IGRA (+)/Cavity (−)/> 35 year 45/184 (24.5) 139/184 (75.5)   2.630 (1.531–4.519)
 IGRA (+)/Cavity (−)/≤ 35 year 118/262 (45.0) 144/262 (55.0)   6.658 (4.083–10.856)
 IGRA (+)/Cavity (+)/> 35 year 10/28 (35.7) 18/28 (64.3)   4.514 (1.869–10.901)
 IGRA (+)/Cavity (+)/≤ 35 year 28/33 (84.8) 5/33 (15.2)   45.500 (16.054–128.955)
  1. TB tuberculosis, BALF bronchoalveolar lavage fluid, IGRA interferon-γ release assays