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Table 1 Demographics and clinical characteristics of HIV-infected patients with PTB

From: Risk factors affecting the mortality of HIV-infected patients with pulmonary tuberculosis in the cART era: a retrospective cohort study in China

  Overall
N = 359
Survivals
N = 280
Deaths
N = 53
P value
Age, Years, median (IQR) 39 (31,52) 39 (29,48) 49 (35,63) < 0.001
Male gender N (%) 325 (90.53%) 254 (90.71%) 48 (90.57%) 1.000
On cART N (%) 98 (27.30%) 83 (29.64%) 8 (15.09%) 0.029
Diagnostic delaya N (%) 153 (42.60%) 106 (37.86%) 36 (67.92%) < 0.001
Extrapulmonary Involvement 49 (13.65%) 35 (12.50%) 12 (22.64%) 0.052
Clinical symptoms
 Fever (> 39 °C) N (%) 263 (73.26%) 207 (73.93%) 32 (60.38%) 0.044
 Cough N (%) 181 (50.42%) 144 (51.43%) 28 (52.83%) 0.851
 Expectoration N (%) 82 (22.84%) 61 (21.79%) 17 (32.08%) 0.105
 Anorexia N (%) 81 (22.56%) 60 (21.45%) 13 (24.53%) 0.617
 Dyspnea N (%) 69 (19.22%) 49 (17.50%) 16 (30.19%) 0.033
Complications
 Bacterial pneumonia N (%) 32 (8.91%) 18 (6.43%) 14 (26.42%) < 0.001
 HBV/HCV co-infection N (%) 25 (6.96%) 19 (6.79%) 6 (11.32%) 0.387
 Syphilis N (%) 33 (9.19%) 30 (10.71%) 1 (1.89%) 0.077
 Diabetes N (%) 14 (3.90%) 11 (3.93%) 2 (3.77%) 1.000
 Hypertension N (%) 12 (3.345%) 9 (3.21%) 2 (3.77%) 1.000
Laboratory examination
 Sputum smear positive N (%) 156 (43.45%) 126 (45.00%) 21 (39.62%) 0.470
 Sputum culture positive N (%) 180 (50.14%) 141 (50.36%) 23 (43.40%) 0.353
 T-spot. TB test positive N (%) 227 (63.23%) 181 (64.64%) 30 (56.60%) 0.265
 HIV RNA lg copies/ml median (IQR) 5.17 (3.91,5.66) 5.14 (3.83,5.65) 5.32 (4.61,5.79) 0.354
 CD4+ T cell/mm3 median (IQR) 51 (23 116) 55 (27 122) 24.5 (10,86) 0.001
Manifestation of lung CT scan
 Extensive pulmonary lesionb N (%) 218 (60.72%) 160 (57.14%) 41 (77.36%) 0.006
 Pulmonary cavity N (%) 36 (10.03%) 25 (8.93%) 9 (16.98%) 0.076
 Pulmonary atelectasis N (%) 31 (8.64%) 20 (7.14%) 9 (16.98%) 0.039
  1. aDiagnostic delay was defined as the pulmonary TB was diagnosed in more than four weeks after the onset of symptoms
  2. bExtensive pulmonary lesion was defined as TB lesions involved more than 3 pulmonary lobes by chest CT scan