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Table 3 Crude onchocerciasis MF prevalence and density in Sierra Leone after five annual rounds of MDA

From: Impact of five annual rounds of mass drug administration with ivermectin on onchocerciasis in Sierra Leone

  Baseline survey 2010 Epidemiological Evaluation Percentage reduction (%) Significance test (P-values)
No. examined MF prev (%) AMD-all (mf/snip) AMD-positive (mf/snip) No. examined MF prevalence (95% CI) AMD-all (mf/snip) (95% CI) AMD-positive (mf/snip) (95% CI) MF prev AMD-all AMD-positive MF prev AMD-all AMD-positive
Overall 7116 53.09 15.33 28.87 5621 21.12 (20.07–22.20) 1.75 (1.48–2.02) 8.29 (7.07–9.50) 60.22 88.58 71.29 0 0 0
By district
 Bo 1499 54.3 18.91 34.82 1079 25.77 (23.24–28.46) 2.95 (2.11–3.80) 11.46 (8.40–14.53) 52.55 84.4 67.09 0 0 0
 Bombali 368 57.88 16.85 29.1 494 16.19 (13.21–19.70) 1.58 (0.86–2.29) 9.72 (5.71–13.72) 72.02 90.62 66.6 0 0 0
 Bonthe 180 40.56 7 17.25 165 26.67 (20.51–33.16) 3.05 (0.41–5.68) 11.42 (1.71–21.13) 34.25 56.43 33.8 0.009 0.004 0.247
 Kailahun 183 49.73 12.06 24.25 118 23.73 (16.96–32.16) 2.01 (0.47–3.55) 8.46 (2.31–14.62) 52.28 83.33 65.11 0 0 0
 Kambia 155 61.94 17.8 28.73 98 23.47 (16.18–32.76) 1.04 (0.43–1.65) 4.41 (2.24–6.58) 62.11 94.16 84.65 0 0 0
 Kenema 286 45.12 6.51 14.42 101 20.79 (14.02–29.70) 1.35 (0.18–2.51) 6.48 (1.09–11.86) 53.9 79.26 55.06 0 0 0.217
 Koinadugu 168 58.33 18.38 31.51 58 6.90 (2.71–16.43) 0.05 (0.00–0.11) 0.75 (0.00–1.55) 88.18 99.73 97.62 0 0 0.005
 Kono 1105 39.01 14.63 37.48 521 9.02 (6.85–11.79) 0.32 (0.18–0.46) 3.53 (2.31–4.75) 76.87 97.81 90.58 0 0 0
 Moyamba 1055 58.2 12.06 20.74 988 29.96 (27.19–32.89) 1.64 (1.27–2.01) 5.46 (4.35–6.58) 48.52 86.4 73.67 0 0 0
 Port Loko 653 57.12 13.83 24.21 738 26.02 (22.98–29.30) 3.10 (1.80–4.40) 11.91 (7.12–16.71) 54.45 77.58 50.81 0 0 0
 Pujehun 560 53.57 9.84 18.36 348 7.76 (5.39–11.03) 0.60 (0.06–1.14) 7.76 (1.03–14.49) 85.52 93.9 57.73 0 0 0.002
 Tonkolili 904 60.4 22.09 36.5 913 16.10 (13.86–18.63) 0.67 (0.43–0.91) 4.16 (2.81–5.50) 73.34 96.97 88.6 0 0 0
By sex
 Male 3461 55.19 21.11 38.16 2805 24.49 (22.94–26.12) 2.55 (2.04–3.06) 10.40 (8.43–12.36) 54.24 87.92 72.75 0 0 0
 Female 3655 51.11 9.94 19.38 2816 17.76 (16.39–19.21) 0.96 (0.77–1.15) 5.40 (4.40–6.40) 64.12 90.34 72.14 0 0 0
Age groups
 1–9 2182 11.05 0.91 8.24 1930 1.71 (1.22–2.39) 0.04 (0.02–0.06) 2.47 (1.49–3.45) 82.55 95.6 70.02 0 0.168 0.02
 10–19 1317 50.57 6.91 13.67 889 16.09 (13.82–18.65) 0.80 (0.51–1.08) 4.94 (3.31–6.58) 66.4 88.42 63.86 0 0 0
 20–29 780 78.21 19.94 25.5 648 38.27 (34.61–42.07) 3.68 (2.48–4.88) 9.58 (6.58–12.58) 49.09 81.54 62.43 0 0 0
 30–39 824 80.95 28.88 35.64 624 37.18 (33.48–41.04) 3.49 (2.34–4.64) 9.38 (6.43–12.33) 52.41 87.92 73.68 0 0 0
 40–49 735 82.31 35.94 43.66 542 38.75 (34.74–42.91) 4.09 (2.65–5.54) 10.56 (6.99–14.13) 51.2 88.62 75.81 0 0 0
 50–59 575 81.39 30.37 37.31 416 37.02 (32.52–41.76) 2.61 (1.15–4.06) 7.04 (3.18–10.89) 52.55 91.41 81.13 0 0 0
  ≥ 60 684 76.17 21.58 28.34 566 29.33 (25.73–33.21) 2.10 (1.47–2.73) 7.17 (5.22–9.12) 59.74 90.27 74.7 0 0 0