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Table 2 E. granulosus worm burdens at day 45 post-infection with in dogs (local Xinjiang breed) vaccinated with rEgM4 and rEgM123 proteins mixed with Quil A

From: Dog vaccination with EgM proteins against Echinococcus granulosus

Group (protein) Dog No. Number of worms
   Total ≤3 seg % ≥4 seg % Gravid Seg %
GST 815 10 228 1063 10.4 9165 89.6 0 0.0
817 17 897 8103 45.3 7528 42.1 2266 12.7
821 22 505 677 3.0 21 828 97.0 0 0.0
822 27 892 11 151 40.0 9529 34.2 7212 25.9
829 42 724 18 311 42.9 12 532 29.3 11 881 27.8
831 26 808 18 762 70.0 8046 30.0 0 0.0
833 9484 839 8.8 8645 91.2 0 0.0
834 34 147 15 618 45.7 12 085 35.4 6444 18.9
837 11 053 927 8.4 10 126 91.6 0 0.0
841 47 079 19 658 41.8 17 424 37.0 9997 21.2
842 31 342 20 582 65.7 4099 13.1 6661 21.3
843 13 535 6178 45.6 4237 31.3 3120 23.1
Average 24 558 10 156 41.4 10 437 42.5 3965 16.1
SD 12 708 8174 5083 4319
Median 24 657 9627 39.0 9347 37.9 2693 10.9
IQR (11 674, 33 446) (961,18 649)   (7787, 2309)   (0,7074)
EgM4 813 34 908 1805 5.2 25 050 71.8 8053 23.1
816 0 0 0 0 0.0 0 0.0
818 11 624 3256 28.0 6271 53.9 2097 18.0
819 0 0 0 0 0.0 0 0.0
820 14 938 12 469 83.5 1696 11.4 773 5.2
826 9939 7982 80.3 1103 11.1 854 8.6
832 0 0 0 0 0.0 0 0.0
838 1796 1796 100.0 0 0.0 0 0.0
840 39 773 27 124 68.2 8897 22.4 3752 9.4
Average 18 830 9072 48.2 7170 38.1 2588 13.7
SD 15 056 9779 9399 2982
Median 9939 1805 18.2 1103 11.1 773 7.8
IQR (0, 24 923) (0, 10 225) (0, 7584) (0, 2925)
Redu%a 59.7 81.3 88.2 71.3
P valueb 0.069 0.219 0.013 0.442
EgM123 814 128 128 100.0 0 0.0 0 0.0
823 1075 1075 100.0 0 0.0 0 0.0
824 0 0 0 0 0.0 0 0.0
825 0 0 0 0 0.0 0 0.0
827 3198 3198 100.0 0 0.0 0 0.0
828 3494 3494 100.0 0 0.0 0 0.0
835 0 0 0 0 0.0 0 0.0
836 408 408 100.0 0 0.0 0 0.0
839 0 0 0 0 0.0 0 0.0
Average 1661 1661 100.0 0 0.0 0 0.0
SD 1580 1580 0 0
Median 128 128 0 0
IQR (0, 2137) (0, 2137) (0, 0) (0, 0)
Redu%a 99.5 98.7 0 100 100
P valueb 0.000 0.002 0.000 0.023
  1. aCompared to those in the GST group. Redu, reduction = (worm burden median in GST-worm burden median in the experiment group)/worm burden median in GST group × 100%. bThe Mann-Whitney U test was used to compare the worm burden median. P value less than 0.05 means that reduction is significant between GST and experimental groups using median analysis. The meaning of a, bis the same in the following tables