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Table 2 E. granulosus worm burdens at day 45 post-infection with in dogs (local Xinjiang breed) vaccinated with rEgM4 and rEgM123 proteins mixed with Quil A

From: Dog vaccination with EgM proteins against Echinococcus granulosus

Group (protein)

Dog No.

Number of worms

  

Total

≤3 seg

%

≥4 seg

%

Gravid Seg

%

GST

815

10 228

1063

10.4

9165

89.6

0

0.0

817

17 897

8103

45.3

7528

42.1

2266

12.7

821

22 505

677

3.0

21 828

97.0

0

0.0

822

27 892

11 151

40.0

9529

34.2

7212

25.9

829

42 724

18 311

42.9

12 532

29.3

11 881

27.8

831

26 808

18 762

70.0

8046

30.0

0

0.0

833

9484

839

8.8

8645

91.2

0

0.0

834

34 147

15 618

45.7

12 085

35.4

6444

18.9

837

11 053

927

8.4

10 126

91.6

0

0.0

841

47 079

19 658

41.8

17 424

37.0

9997

21.2

842

31 342

20 582

65.7

4099

13.1

6661

21.3

843

13 535

6178

45.6

4237

31.3

3120

23.1

Average

24 558

10 156

41.4

10 437

42.5

3965

16.1

SD

12 708

8174

5083

4319

Median

24 657

9627

39.0

9347

37.9

2693

10.9

IQR

(11 674, 33 446)

(961,18 649)

 

(7787, 2309)

 

(0,7074)

EgM4

813

34 908

1805

5.2

25 050

71.8

8053

23.1

816

0

0

0

0

0.0

0

0.0

818

11 624

3256

28.0

6271

53.9

2097

18.0

819

0

0

0

0

0.0

0

0.0

820

14 938

12 469

83.5

1696

11.4

773

5.2

826

9939

7982

80.3

1103

11.1

854

8.6

832

0

0

0

0

0.0

0

0.0

838

1796

1796

100.0

0

0.0

0

0.0

840

39 773

27 124

68.2

8897

22.4

3752

9.4

Average

18 830

9072

48.2

7170

38.1

2588

13.7

SD

15 056

9779

9399

2982

Median

9939

1805

18.2

1103

11.1

773

7.8

IQR

(0, 24 923)

(0, 10 225)

(0, 7584)

(0, 2925)

Redu%a

59.7

81.3

88.2

71.3

P valueb

0.069

0.219

0.013

0.442

EgM123

814

128

128

100.0

0

0.0

0

0.0

823

1075

1075

100.0

0

0.0

0

0.0

824

0

0

0

0

0.0

0

0.0

825

0

0

0

0

0.0

0

0.0

827

3198

3198

100.0

0

0.0

0

0.0

828

3494

3494

100.0

0

0.0

0

0.0

835

0

0

0

0

0.0

0

0.0

836

408

408

100.0

0

0.0

0

0.0

839

0

0

0

0

0.0

0

0.0

Average

1661

1661

100.0

0

0.0

0

0.0

SD

1580

1580

0

0

Median

128

128

0

0

IQR

(0, 2137)

(0, 2137)

(0, 0)

(0, 0)

Redu%a

99.5

98.7

0

100

100

P valueb

0.000

0.002

0.000

0.023

  1. aCompared to those in the GST group. Redu, reduction = (worm burden median in GST-worm burden median in the experiment group)/worm burden median in GST group × 100%. bThe Mann-Whitney U test was used to compare the worm burden median. P value less than 0.05 means that reduction is significant between GST and experimental groups using median analysis. The meaning of a, bis the same in the following tables