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Table 3 E. granulosus worm burdens at day 45 post-infection with in dogs (local Xinjiang breed) vaccinated with rEgM9 and rEgM123 proteins coupled with ISCOMs

From: Dog vaccination with EgM proteins against Echinococcus granulosus

Group (protein) Dog No. Number of worms
   Total ≤3 seg % ≥4 seg % Gravid Seg %
GST control 802 24 618 24 618 100.0 0 0.0 0 0.0
810 15 273 15 273 100.0 0 0.0 0 0.0
811 2784 2784 100.0 0 0.0 0 0.0
1313 41 288 22 857 55.4 18 431 44.6 0 0.0
1314 11 547 7362 63.8 4185 36.2 0 0.0
Average 19 102 14 579 76.3 11 308 59.2 0 0.0
SD 14 669 9500 10 073 0
Median 15 273 15 273 0 0
IQR (7166, 32 953) (5073,23 738) (0, 11 308) (0,0)
EgM9 804 41 573 6214 14.9 35 359 85.1 0 0.0
808 59 8 13.6 51 86.4 0 0.0
848 13 262 13 262 100.0 0 0.0 0 0.0
849 2933 2933 100.0 0 0.0 0 0.0
Average 14 457 5604 38.8 8853 61.2 0 0.0
SD 18 946 5700 24 967 0
Median 8098 4574 26 0
IQR (778, 34 495) (739, 11 500) (0, 26 532) (0,0)
Redu%a 47.0 59.3 -100 0
P valueb 0.624 0.142 0.788 1.000
EgM123 803 5729 5729 100.0 0 0.0 0 0.0
806 12 058 12 058 100.0 0 0.0 0 0.0
812 28 28 100.0 0 0.0 0 0.0
847 1653 301 18.2 1352 81.8 0 0.0
850 23 23 100.0 0 0.0 0 0.0
Average 3898 3628 93.1 270 34.7 0 0.0
SD 5123 5303 604 0
Median IQR 1653 (26, 8894) 301 (26, 8894) 0 (0,676) 0 (0,0)
Redu%a 89.2 98.0 0 0
IQR (26,8894) (26, 8894)   (0, 676)   (0, 0)  
P valueb 0.047 0.047 0.368 1.000
  1. aCompared to those in the GST group. Redu, reduction = (worm burden median in GST-worm burden median in the experiment group)/worm burden median in GST group × 100%. bThe Mann-Whitney U test was used to compare the worm burden median. P value less than 0.05 means that reduction is significant between GST and experimental groups using median analysis. The meaning of a, bis the same in the following tables