Skip to main content

Table 1 Summary of included references evaluating risk factors for cholangiocarcinoma

From: Thinking beyond Opisthorchis viverrini for risk of cholangiocarcinoma in the lower Mekong region: a systematic review and meta-analysis

Reference

Year

Country

Source of patients or samples

Study design

Sample size: cases/controls

Risk factor categories reported

Measure of effect

Parkin et al. [22]

1991

Thailand

Maharat Nakorn Ratchasima Hospital, Ubon Ratchathani Hospital, National Cancer Institute

case-control

103/103

behaviors, socioeconomics, diet, immune response, other infection

odds ratio

Itoh et al. [35]

1994

Thailand/ Japan

Khon Kaen province hospitals, Japan

case-control

47/68

immune response, gender

mean or proportion difference

Haswell-Elkins et al. [46]

1994

Thailand

Villages in Khon Kaen and Mahasarkham provinces

cross-sectional survey

15 CCA cases of 1807 patients screened

gender

odds ratio

Honjo et al. [23]

2005

Thailand

Nakhon Phanom province hospitals

case-control

129/129

behaviors, socioeconomics, diet, genetics, treatment

odds ratio

Jinawath et al. [31]

2006

Thailand/ Japan

Srinagarind Hospital and Kyoto University Hospital

case-control

20/10

genetics

median gene expression

Marahatta et al. [55]

2006

Thailand

LFCRC Repositorya

case-control

30/30

genetics

odds ratio

Prawan et al. [29]

2005

Thailand

Srinagarind Hospital

case-control

216/233

genetics

odds ratio

Poomphakwaen et al. [2]

2009

Thailand

Khon Kaen Cohort Study

nested case-control

108/108

behaviors, diet, treatment, genetics

odds ratio

Srivatanakul et al. [38]

2010

Thailand

Nakhon Phanom province hospitals

case-control

106/106

other infections, immune response

odds ratio

Songserm et al. [27]

2011

Thailand

Khon Kaen Cohort Study

nested case-control

219/438

genetics, diet, socioeconomics

odds ratio

Sripa et al. [37]

2012

Thailand

Khon Kaen area villages, non-OV endemic Thailand, LFCRC Repositorya

case-control

121/21

immune response

odds ratio

Yongvanit et al. [32]

2012

Thailand

Khon Kaen province hospitals

case-control

13/10

genetics

mean difference

Songserm et al. [24]

2012

Thailand

Khon Kaen Cohort Study

nested case-control

219/438

behaviors, socioeconomics, diet, genetics

odds ratio

Zeng et al. [30]

2013

Thailand

Ubon Ratchathani Cancer Center Hospital

case-control

105/105

genetics

odds ratio

Manwong et al. [25]

2013

Thailand

Sappasit Prasong Hospital and Ubon Ratchathani Cancer Center

case-control

123/123

socioeconomics, diet, treatment, behaviors, immune response

odds ratio

Plieskatt et al. [33]

2014

Thailand

LFCRC Repositorya

case-control

16/13

genetics

mean difference

Songserm et al. [26]

2014

Thailand

Khon Kaen Cohort Study

case-control

219/438

behaviors, genetics

odds ratio

Prayong et al. [34]

2014

Thailand

Srinagarind Hospital and community

case-control

79/80

genetics

odds ratio

  1. aLiver Fluke and Cholangiocarcinoma Research Center (LFCRC) Biological Repository, Khon Kaen University, Thailand