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Table 2 Laboratory test results for cases and controls

From: Onchocerca volvulus as a risk factor for developing epilepsy in onchocerciasis endemic regions in the Democratic Republic of Congo: a case control study

 

Cases

Controls

 

Draju, Logo

(Ituri)

Rassia, Rethy

(Ituri)

Salambongo, Wanierukula (Tshopo)

Draju, Logo

(Ituri)

Rassia, Rethy

(Ituri)

Salambongo, Wanierukula (Tshopo)

P valuee (a,b,c,d)

Skin biopsy test positivef

56%

(33/59)

35%

(17/49)

79%

(53/67)

26%

(17/65)

20%

(9/45)

67%

(36/54)

0.001, 0.166, 0.149, <  0.001

Mean (range) mf loadg

31.79

(0–352.00)

9.71

(0–220.00)

27.88

(0–204.50)

2.74 (0–78.00)

3.46 (0–59.50)

18.50

(0–132.00)

<  0.001, 0.246, 0.211, <  0.001

O volvulus IgG4 antibodies

51%

(30/59)

43%

(21/49)

42%

(28/67)

22%

(14/65)

20%

(9/45)

44%

(26/59)

<  0.001, 0.026, 0.858, 0.002

  1. MF microfilariae load
  2. a comparison between cases and controls for Logo Health zone
  3. b comparison between cases and controls for Rethy Health zone
  4. c comparison between cases and controls for Wanierukula Health zone
  5. d comparison between cases and controls for all three Health zones
  6. eFisher’s exact test was done for testing equality of two proportions and t-test used for testing equality of two means
  7. fSkin biopsy test was considered positive if at least one microfilaria was found in either of the two skin biopsies
  8. gMean number of mf per mg skin