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Table 1 Baseline characteristics of 919 children enrolled in the study

From: Parasite reduction ratio one day after initiation of artemisinin-based combination therapies and its relationship with parasite clearance time in acutely malarious children

Variables AA
(n = 295)
AL
(n = 303)
DHP
(n = 321)
All
(n = 919)
P value
Male:Female 153:142 159:144 183:138 495:424 0.37
Age (month)
 Mean 39 40.5 38.5 39.3 0.3
 95% CI 37.2–40.9 38.6–42.3 36.6–40.3 38.3–40.4  
 No. ≤ 12 months (%) 23 (7.8) 18 (5.9) 29 (9) 70 (7.6) 0.35
Duration of illness (day)
 Mean 4.2 3.8 3.9 4 0.54
 95% CI 3.7–4.7 3.3–4.3 3.5–4.3 3.7–4.2  
Weight (kg)
 Mean 13.4 13.5 13.3 13.3 0.18
 95% CI 13–13.9 13–14 13–13.6 13–13.6  
Temperature (°C)
 Mean 37.8 37.9 37.8 37.8 0.44
 95% CI 37.6–37.9 37.8–38 37.7–37.9 37.7–37.9  
No. with
  ≥ 37.5 °C (%)* 182 (61.7) 195 (64.4) 193 (60.1) 570 (62) 0.55
  ≥ 40 °C (%) 21 (7) 22 (7.3) 28 (8.7) 81 (8.8) 0.37
Haematocrit (%)
 Mean 30.5 30.3 30.9 30.6 0.3
 95% CI 29.9–31.1 29.7–30.9 30.3–31.5 30.3–30.9  
No with anaemia (%) 113 (38.3) 120 (39.6) 104 (32.4) 337 (36.7) 0.16
 Mild (%) 106 (35.9) 110 (36.3) 91 (28.3) 307 (33.4) 0.06
 Moderate (%) 6 (2) 10 (3.3) 13 (4) 29 (3.2) 0.35
 Severe (%) 1 (0.3) 0 (0) 0 (0) 1 (0.1)
Parasitaemia (/μl)
 Geometric mean 15 518 16 254 15 185 15 638 0.87
 Range 2000–200 000 2003–200 000 2000–200 000 2000–200 000  
 Gametocytaemia (%) 20 (6.8) 9 (3) 19 (5.9) 48 (5.2) 0.09
  1. *Overall, 570 children were febrile at presentation. Geometric mean enrolment parasitaemia was significantly higher in febrile compared to non-febrile children (20 506/μl [range: 2000–200 000; n = 570] versus 10 045/μl [2000–198 200; n = 349], respectively; P < 0.0001)
  2. AL: Artemether-lumefantrine; AA: Artesunate-amodiaquine; DHP: Dihydroartemisinin-piperaquine; CI: Confidence interval