Variable | Total No. | No. with PRRD1 > 5000 | OR (95% CI) | P value | aOR (95% CI) | P value |
---|---|---|---|---|---|---|
Gender | ||||||
 Female | 424 | 119 | 1 |  |  |  |
 Male | 495 | 135 | 1.0 (0.7–1.3) | 0.85 | – | – |
Age (month) | ||||||
  ≤ 15 | 103 | 19 | 1 |  | 1 |  |
  > 15 | 810 | 232 | 1.8 (1.1–3.0) | 0.04 | 2.0 (1.0–4.1) | 0.048 |
Duration of illness (days) | ||||||
  ≤ 2 | 269 | 82 | 1 |  |  |  |
  > 2 | 334 | 121 | 1.3 (0.9–1.8) | 0.16 | – | – |
Haematocrit at presentation (%) | ||||||
  < 30 | 652 | 170 | 1 |  | 1 |  |
  ≥ 30 | 247 | 83 | 1.4 (1.0–2.0) | 0.03 | 1.2 (0.8–1.9) | 0.3 |
Haematocrit on day 1 (%) | ||||||
  ≥ 30 | 483 | 130 | 1 |  |  |  |
  < 30 | 407 | 120 | 1.1 (0.8–1.5) | 0.44 | – | – |
History of fever before treatment | ||||||
 Absent | 170 | 41 | 1 |  |  |  |
 Present | 749 | 213 | 1.3 (0.9–1.9) | 0.3 | – | – |
Temperature at presentation (°C) | ||||||
  ≤ 37.4 | 349 | 88 | 1 |  |  |  |
  > 37.4 | 570 | 166 | 1.2 (0.9–1.6) | 0.23 | – | – |
Fever on day 1* | ||||||
 Absent | 797 | 225 | 1 |  |  |  |
 Present | 103 | 26 | 0.9 (0.5–1.4) | 0.6 | – | – |
Enrolment Parasitaemia | ||||||
  ≤ 104 | 370 | 44 | 1 |  | 1 |  |
  > 104 | 349 | 210 | 4.6 (3.2–6.6) | < 0.0001 | 4.8 (3.0–7.5) | < 0.0001 |
Gametocytaemia | ||||||
 Absent | 871 | 243 | 1 |  |  |  |
 Present | 48 | 11 | 0.8 (0.4–1.5) | 0.56 | – | – |
Drug treatment | ||||||
 AL | 303 | 68 | 1 |  |  |  |
 AA | 295 | 85 | 1.4 (1.0–2.0) | 0.09 | – | – |
 DHP | 321 | 101 | 1.6 (1.1–2.3) | 0.01 | 1.8 (1.2–2.6) | 0.003 |