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Table 2 Concordance (coefficient kappa) and accuracy analysis between Kato-Katz test results obtained by an increasing number of slides and the results of one rapid urine test sample (POC-CCA)

From: Concordance of the point-of-care circulating cathodic antigen test for the diagnosis of intestinal schistosomiasis in a low endemicity area

POC-CCA

Kato-Katz 1S 1st AS

Kato-Katz 6S 3SA

Kato-Katz 16S 3SA

Positive

Negative

Total

Positive

Negative

Total

Positive

Negative

Total

Positive

5

84

89

14

75

89

23

66

89

Negative

4

279

283

10

273

283

12

271

283

Total

9

363

372

24

348

372

35

337

372

Sensitivity

55.6% (95% CI: 26.6–81.1)

58.3% (95% CI: 38.8–75.5)

65.7% (95% CI: 49.1–79.1)

Specificity

76.9% (95% CI: 72.2–80.9)

78.4% (95% CI: 73.8–82.4)

80.4% (95% CI: 75.8–84.3)

PPV

6.0% (95% CI: 2.4–12.5)

16.0% (95% CI: 9.6–24.6)

26.0% (95% CI: 17.9–37.0)

NPV

98.6% (95% CI: 96.4–99.4)

96.5% (95% CI: 93.6–98.1)

95.8% (95% CI: 92.7–97.6)

Kappa index

0.06 (95% CI: 0.01–0.1)

0.16 (95% CI: 0.1–0.2)

0.27 (95% CI: 0.2–0.3)

Accuracy

76.0% (95% CI: 74.6–82.8)

77.0% (95% CI: 72.6–81.1)

79.0 79.0% (95% CI: 74.6–82.8)

  1. CI Confidence interval, PPV Positive predictive value, NPV Negative predictive value, S Slides, SA Sample, 1S 1st SA One slide of the first sample, 6S 3SA Six slides of three different samples, two slides of each sample, 16S 3SA 16 slides of three different samples, 12 slides of the first sample, two slides of the second sample and two slides of the third sample