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Table 2 Characteristics of HBsAg-positive mothers and their HBV-exposed children in four provinces, China 2016–2017

From: Outcomes of the national programme on prevention of mother-to-child transmission of hepatitis B virus in China, 2016–2017

Characteristics N %
Total 4112 100.0
Province
 Guangdong 1297 31.5
 Hebei 920 22.4
 Shaanxi 718 17.5
 Zhejiang 1177 28.6
Maternal age (years)
 18–24 280 6.8
 25–34 2992 72.8
 35–45 840 20.4
Maternal educational level
 Junior middle school and below 1382 33.6
 High middle school and above 2730 66.4
Maternal residence rural/urban
 Rural 2818 68.5
 Urban 1294 31.5
Maternal Parity
 1 1732 42.1
  > 1 2380 57.9
Maternal HBeAg status during this pregnancy
 Positive 1221 29.7
 Negative 2740 66.6
 Unknown 151 3.7
Maternal HBV DNA during this pregnancy (IU/ml)
  < 100 182 4.4
 100–2 000 000 574 14.0
  > 2 000 000 291 7.1
 Unknown 3065 74.5
Maternal antiviral treatment during this pregnancy
 Yes 392 9.5
 No 3720 90.5
Level of delivery hospital
 County level and below 2594 63.1
 Prefectural and above 1518 36.9
Mode of delivery
 Vaginal delivery 2349 57.1
 Caesarean section 1763 42.9
Child age (months)
 7–12 1626 63.1
 13–22 2486 36.9
Child gender
 Male 2185 53.1
 Female 1927 46.9
Gestational age (weeks)
  < 37 236 5.7
 37–43 3876 94.3
Child birth weight (g)
  < 2500 (LBW) 131 3.2
 2500–5400 3981 96.8
Interval between birth and HBvacc-BD (hours)
  < 12 3579 87.0
 12–24 466 11.3
  > 24 67 1.7
Type of HBvacc-BD
 10 μg yeast vaccine 3637 88.5
 20 μg CHO vaccine 285 6.9
 10 μg CHO vaccine 190 4.6
Interval between birth and HBIG dose (hours)
  < 12 3888 94.6
 12–24 182 4.4
  > 24 22 0.5
 No 20 0.5
Received both HBvacc birth dose and HBIG within 12 h of birth
 Yes 3538 86.0
 No 574 14.0
Interval between third dose HBvacc and HBV serological test (months)
  < 7 1666 40.5
 7–18 2446 59.5
  1. HBsAg hepatitis B surface antigen, HBV hepatitis B virus, HBeAg hepatitis B e antigen, HBvacc hepatitis B vaccine, HBvacc-BD hepatitis B vaccine birth dose, HBIG hepatitis B immunoglobulin, LBW low birth weight, CHO Chinese hamster ovary, IU international unit