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Table 2 Characteristics of HBsAg-positive mothers and their HBV-exposed children in four provinces, China 2016–2017

From: Outcomes of the national programme on prevention of mother-to-child transmission of hepatitis B virus in China, 2016–2017

Characteristics

N

%

Total

4112

100.0

Province

 Guangdong

1297

31.5

 Hebei

920

22.4

 Shaanxi

718

17.5

 Zhejiang

1177

28.6

Maternal age (years)

 18–24

280

6.8

 25–34

2992

72.8

 35–45

840

20.4

Maternal educational level

 Junior middle school and below

1382

33.6

 High middle school and above

2730

66.4

Maternal residence rural/urban

 Rural

2818

68.5

 Urban

1294

31.5

Maternal Parity

 1

1732

42.1

  > 1

2380

57.9

Maternal HBeAg status during this pregnancy

 Positive

1221

29.7

 Negative

2740

66.6

 Unknown

151

3.7

Maternal HBV DNA during this pregnancy (IU/ml)

  < 100

182

4.4

 100–2 000 000

574

14.0

  > 2 000 000

291

7.1

 Unknown

3065

74.5

Maternal antiviral treatment during this pregnancy

 Yes

392

9.5

 No

3720

90.5

Level of delivery hospital

 County level and below

2594

63.1

 Prefectural and above

1518

36.9

Mode of delivery

 Vaginal delivery

2349

57.1

 Caesarean section

1763

42.9

Child age (months)

 7–12

1626

63.1

 13–22

2486

36.9

Child gender

 Male

2185

53.1

 Female

1927

46.9

Gestational age (weeks)

  < 37

236

5.7

 37–43

3876

94.3

Child birth weight (g)

  < 2500 (LBW)

131

3.2

 2500–5400

3981

96.8

Interval between birth and HBvacc-BD (hours)

  < 12

3579

87.0

 12–24

466

11.3

  > 24

67

1.7

Type of HBvacc-BD

 10 μg yeast vaccine

3637

88.5

 20 μg CHO vaccine

285

6.9

 10 μg CHO vaccine

190

4.6

Interval between birth and HBIG dose (hours)

  < 12

3888

94.6

 12–24

182

4.4

  > 24

22

0.5

 No

20

0.5

Received both HBvacc birth dose and HBIG within 12 h of birth

 Yes

3538

86.0

 No

574

14.0

Interval between third dose HBvacc and HBV serological test (months)

  < 7

1666

40.5

 7–18

2446

59.5

  1. HBsAg hepatitis B surface antigen, HBV hepatitis B virus, HBeAg hepatitis B e antigen, HBvacc hepatitis B vaccine, HBvacc-BD hepatitis B vaccine birth dose, HBIG hepatitis B immunoglobulin, LBW low birth weight, CHO Chinese hamster ovary, IU international unit