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Table 2 The accuracy performance of RDBH assay compared to phenotypic DST in Mycobacterium tuberculosis clinical strains

From: Accuracy of a reverse dot blot hybridization assay for simultaneous detection of the resistance of four anti-tuberculosis drugs in Mycobacterium tuberculosis isolated from China

Drug

Phenotypic DST

RDBH assay

R

S

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Concordance (%)

Kappa value

RIF

R

171

14

92.4

98.5

98.8

90.5

95.0

0.90

 

S

2

133

      

INH

R

186

20

90.3

97.3

98.4

84.7

92.8

0.85

 

S

3

111

      

SM

R

120

35

77.4

91.5

90.0

81.1

84.7

0.69

 

S

14

151

      

EMB

R

51

32

61.4

82.7

55.4

86.0

77.2

0.43

 

S

41

196

      
  1. S Susceptible, R Resistant, PPV Positive predictive value, NPV Negative predicte value, RIF Rifampicin, INH Isoniazid, SM Streptomycin, EMB Ethambutol, RDBH Reverse dot blot hybridization, DST Drug susceptibility testing
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Infectious Diseases of Poverty

ISSN: 2049-9957

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