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Table 3 The accuracy performance of RDBH assay compared to sequencing in Mycobacterium tuberculosis clinical strains

From: Accuracy of a reverse dot blot hybridization assay for simultaneous detection of the resistance of four anti-tuberculosis drugs in Mycobacterium tuberculosis isolated from China

DrugSequencingRDBH assay
RSSensitivity (%)Specificity (%)PPV (%)NPV (%)Concordance (%)Kappa value
RIFM170497.797.998.397.397.80.96
 W3143      
INHM189497.9100.0100.096.998.80.97
 W0127      
SMM134397.8100.0100.098.499.10.98
 W0183      
EMBM901982.699.197.891.793.40.85
 W2209      
  1. M Mutated, W Wild type, S Susceptible, R Resistant, PPV Positive predictive value; NPV, Negative predicte value, RIF Rifampicin, INH Isoniazid, SM Streptomycin, EMB Ethambutol, RDBH Reverse dot blot hybridization