Improvement cues of lesion absorption using the adjuvant therapy of traditional Chinese medicine Qinbudan tablet for retreatment pulmonary tuberculosis with standard anti-tuberculosis regimen

Zhang, Shao-Yan; Fu, Ji-You; Guo, Xiao-Yan; Wu, Ding-Zhong; Zhang, Tong; Li, Cui; Qiu, Lei; Shao, Chang-Rong; Xiao, He-Ping; Chu, Nai-Hui; Deng, Qun-Yi; Zhang, Xia; Yan, Xiao-Feng; Wang, Zhao-Long; Zhang, Zhi-Jie; Jiang, Xin; Zheng, Yue-Juan; Zheng, Pei-Yong; Zhang, Hui-Yong; Lu, Zhen-Hui

doi:10.1186/s40249-020-00660-z

Table 2 Baseline characteristics of the study population

From: Improvement cues of lesion absorption using the adjuvant therapy of traditional Chinese medicine Qinbudan tablet for retreatment pulmonary tuberculosis with standard anti-tuberculosis regimen

Characteristics		Placebo n = 88 (%)	QBDT n = 93 (%)	Statistics^a/b	P value
Sociodemographic characteristics
Gender^a	Male	57 (64.8)	60 (64.5)	0.00	0.97
Gender^a	Female	31 (35.2)	33 (35.5)
Source of patients	Outpatient	29 (33.0)	36 (38.7)	0.65	0.42
Source of patients	Inpatient	59 (67.0)	57 (61.3)
Marital status	Unmarried	30 (34.1)	34 (36.6)	0.12	0.73
Marital status	Married	58 (65.9)	59 (63.4)
Occupation	Worker	13 (14.8)	16 (17.2)	4.84	0.85
	Farmer	15 (17.0)	13 (14.0)
	Cadre	3 (3.4)	4 (4.3)
	Intellectual	1 (1.1)	3 (3.2)
	Soldier	2 (2.3)	3 (3.2)
	Staff member	10 (11.4)	11 (11.8)
	Self-employed	5 (5.7)	7 (7.5)
	Retired	11 (12.5)	5 (5.4)
	Unemployed	19 (21.6)	23 (24.7)
	Other	9 (10.2)	8 (8.6)
Education level	Primary school	16 (18.2)	14 (15.1)	1.20	0.75
	Junior high school	31 (35.2)	33 (35.5)
	Senior middle School	20 (22.7)	27 (29.0)
	University and more	21 (23.9)	19 (20.4)
Age^b	Mean ± SD	39.30 ± 14.95	37.72 ± 15.33	0.70	0.49
Height (cm)	Mean ± SD	166.96 ± 6.56	167.83 ± 8.80	0.75	0.45
Weight (kg)	Mean ± SD	56.05 ± 10.06	55.77 ± 10.08	0.19	0.85
Complications	No	68 (77.3)	77 (82.8)	0.87	0.35
Complications	Yes	20 (22.7)	16 (17.2)
Clinical course	Mean ± SD	35.18 ± 47.02	37.72 ± 46.30	0.37	0.72
Laboratory and imaging examination
Sputum smear and culture	Culture+ smear+	74 (84.1%)	81 (87.1%)	0.33	0.56
Sputum smear and culture	Culture+ smear-	14 (15.9%)	12 (12.9%)
Drug resistance	Pyrazinamide	15 (17.0%)	22 (23.7%)	1.22	0.27
	Ethambutol	17 (19.3%)	15 (16.1%)	0.32	0.57
	Streptomycin	12 (13.6%)	11 (11.8%)	0.13	0.72
Lung lesion	Normal	0 (0.0)	0 (0.0)	0	1.00
Lung lesion	Abnormal	88 (100.0)	93 (100.0)
Cavitation	No	36 (40.9)	42 (45.2)	0.33	0.56
Cavitation	Yes	52 (59.1)	51 (54.8)

Note: ^achi-square test, statistics value, χ²; ^brank sum test statistics value, Z; QBDT: Qinbudan tablet; CT: Computed tomography

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ISSN: 2049-9957

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