Fig. 3

MSTs illustrating the phylogenetic pathways. The MST connects each genotype based on degree of changes required to go from one allele to another; The lines denotes the number of allele changes between two patterns: less than three changes (solid lines), four changes (gray dashed lines) and five or more changes (gray dotted lines); The size of the circle is proportional to the quantities of isolates sharing same pattern. MST: Minimum Spanning Tree; CAS: Central-Asian family; H: Haarlem family; LAM: Latin American and Mediterranean family; EAI: East-African Indian family; TSL: T sub-lineage; BSP: Beijing sub-pedigree