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Table 1 Comparison of nodule characteristics between lung metastasis and hematogenous disseminated tuberculosis

From: Misdiagnosis of a multi-organ involvement hematogenous disseminated tuberculosis as metastasis: a case report and literature review

 

Lung metastasis [35, 36]

Hematogenous disseminated tuberculosis (HDTB) [37, 38]

Sources

Hematogenous

Hematogenous

Cancer history

Yes

No

Anatomical distribution

Scatter within two lung fields, but mostly distribute in the middle and lower lung field and surround subpleural lung tissues.

Acute HDTB

Subacute or chronic HDTB

Randomly and evenly distribute in both lung fields

Randomly scatter in the two lung fields without uniformity the upper middle lung is more common

Nature

Solid density, ground glass density, or mixed density

Uniform density

Uneven density, may display tuberculous globules, or tuberculoma

Size

Variable

Uniform size, more miliary nodules

Variable

Boundary

Most of nodules have clear boundaries, but part of them not, showing cavity or ground glass opacity

Clear

Not clear, may display cavity or ground glass opacity

Accompanying symptoms

Mediastinal lymph node enlargement and pleural effusion

Mediastinal lymph node enlargement