Rising challenge of multidrug-resistant tuberculosis in China: a predictive study using Markov modeling

Table 1 State descriptions and initial data set among the cohort of 100 000 people

	Description	Population at start	Sources
Uninfected	Individuals without TB infection (latent or active)	79 948	Wang LX [16]
DS LTBI	Individuals with latent infection of DS-TB	18 627	Wang LX [16], Gao L [17], Li X [18]
MDR LTBI	Individuals with latent infection of MDR-TB	1359	Wang LX [16], Gao L [17], Li X [18]
DS-TB⁺ untreated	Active DS-TB⁺ cases not treated with TB regimens	62	Wang LX [16]
MDR-TB untreated	Active MDR-TB cases not treated with MDR-TB regimens	4	Wang LX [16]
DS-TB⁺ treated	Active DS-TB⁺ cases undergoing treatments	0	Starting from 2012 (the second cycle of the model)
MDR-TB treated	Active MDR-TB cases undergoing MDR-TB treatment	0	Starting from 2012 (the second cycle of the model)
Deceased	Deaths from 100 000 population	0	Starting from 2012 (the second cycle of the model)

DS drug-susceptible; TB tuberculosis; DS-TB drug-susceptible tuberculosis; LTBI latent tuberculosis infection; MDR multidrug-resistant; MDR-TB multidrug-resistant tuberculosis; DS-TB⁺ bacteriologically confirmed drug-susceptible tuberculosis

ISSN: 2049-9957