Table 2 MIC range, MIC50, and MIC90 of 10 antimicrobial agents against 25 B. melitensis strains
Antibiotic | MIC (μg/ml) | Classification of isolates, 1No. (%) | Breakpoints (μg/ml) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Range | 50%†| 90%†| S | I | R | S | I | R | |
Doxycycline | 0.12–0.24 | 0.12 | 0.12 | 25 (100) | 0 | 0 | ≤ 1 | – | – |
Tetracycline | 0.25–1 | 0.25 | 0.5 | 25 (100) | 0 | 0 | ≤ 1 | – | – |
Gentamicin | 0.5–1 | 0.5 | 1.0 | 25 (100) | 0 | 0 | ≤ 4 | – | – |
Ciprofloxacin | 0.5–1 | 0.5 | 1.0 | 25 (100) | 0 | 0 | ≤ 1 | – | – |
Ofloxacin | 1.0 | 1.0 | 1.0 | 25 (100) | 0 | 0 | ≤ 2 | – | – |
Moxifloxacin | 1.0 | 1.0 | 1.0 | 25 (100) | 0 | 0 | ≤ 1 | – | – |
Streptomycin | 2–4 | 2.0 | 4.0 | 25 (100) | 0 | 0 | ≤ 8 | – | – |
Rifampin | 0.08–3.2 | 0.5 | 1.0 | 21 (84) | 4 (16) | 0 | ≤ 1 | 2 | ≥ 4 |
Cotrimoxazole | 1/19–4/76 | 2/38 | 4/76 | 20 (80) | 0 | 5 (20) | ≤ 2/38 | – | – |
Azithromycin | 16–64 | 64 | 64 | 0 | 0 | 25 (100) | ≤ 4 | – | – |