Fig. 2

Percentages of Th1, Th2, Tc1, and Tc2 in samples from patients with acute brucellosis pre-and post-treatment and healthy controls. a, b, c and d Comparisons of the percentages of Th1, Th2, Tc1, and Tc2 cells (Th1: CD4 + IFN-γ + T cells, Th2: CD4 + IL-4 + T cells, Tc1: CD8 + IFN-γ + T cells, Tc2: CD8 + IL-4 + T cells) in healthy controls (HC) and patients with acute disease before treatment (Pre-treatment) and after treatment (Post-treatment) (n = 28, 21, and 21, respectively) are shown. The vertical line represents the median. A Mann–Whitney U-test was performed to compare controls and patients, and pre- and post-treatment values for patients were compared by the Wilcoxon matched-pair signed-rank test. HC: healthy control