Table 3 Univariate and adjusted Logistic regression analysis of OR of incomplete suppression among 758 treatment-naïve patients initiating NNRTI-based ART
Variable | Univariate analysis | Adjusted analysis † | ||||
|---|---|---|---|---|---|---|
OR | (95% CI) | P value | OR | (95% CI) | P value | |
Male gender | 1.608 | (0.861–3.004) | 0.136 | 1.533 | (0.805–2.917) | 0.193 |
Age | 0.993 | (0.969–1.018) | 0.595 | – | – | – |
Year of ART initiation | 0.743 | (0.448–1.230) | 0.248 | – | – | – |
Baseline RNA (copies/ml) | ||||||
< 100 000 | 1.000 | – | – | 1.000 | – | – |
100 000–500 000 | 2.937 | (1.712–5.041) | < 0.001 | 2.736 | (1.577–4.747) | < 0.001 |
≥ 500 000 | 6.458 | (3.061–13.625) | < 0.001 | 6.084 | (2.761–13.407) | < 0.001 |
Baseline CD4 (cells/m3) | ||||||
< 100 | 1.000 | – | – | 1.000 | – | – |
1.057 | (0.809–1.383) | 0.014 | 1.386 | (0.633–3.307) | 0.414 | |
200–350 | 1.227 | (0.970–1.551) | 0.004 | 0.970 | (0.457–2.059) | 0.938 |
> 350 | 1.313 | (0.016–1.697) | 0.120 | 0.478 | (0.190–1.206) | 0.118 |
HBsAg (+) | 1.246 | (0.612–2.536) | 0.545 | – | – | – |
HCV-Ab (+) | 1.197 | (0.350–4.093) | 0.774 | – | – | – |
Mode of transmission | 1.029 | (0.734–1.444) | 0.866 | – | – | – |
HIV subtype | 1.306 | (0.631–2.705) | 0.472 | – | – | – |
Resistance (low, intermediate and high) | 1.543 | (0.328–7.261) | 0.583 | – | – | – |