Table 4 Univariate and adjusted Logistic regression analysis of OR of viral rebound after excluding blips among 758 treatment-naïve patients initiating NNRTI-based ART
Variable | Univariate analysis | Adjusted analysis a | ||||
|---|---|---|---|---|---|---|
OR | (95% CI) | P value | OR | (95% CI) | P value | |
Male gender | 1.259 | (0.461–3.440) | 0.653 | – | – | – |
Age | 0.976 | (0.932–1.021) | 0.286 | – | – | – |
Year of ART initiation | 0.551 | (0.267–1.137) | 0.107 | – | – | – |
Baseline RNA (copies/ml) | ||||||
< 100 000 | 1.000 | – | – | 1.000 | – | – |
100 000–500 000 | 2.781 | (1.113–6.950) | 0.029 | 2.405 | (0.943–6.133) | 0.066 |
≥500 000 | 5.182 | (1.592–17.555) | 0.008 | 3.671 | (1.009–13.355) | 0.048 |
Baseline CD4 (cells/m3) | ||||||
< 100 | 1.000 | – | – | 1.000 | – | – |
100–200 | 0.781 | (0.254–2.402) | 0.666 | 0.936 | (0.297–0.946) | 0.910 |
200–350 | 0.318 | (0.104–0.971) | 0.044 | 0.469 | (0.144–1.524) | 0.208 |
> 350 | 0.250 | (0.061–1.024) | 0.054 | 0.350 | (0.082–1.494) | 0.156 |
HBsAg (+) | 2.049 | (0.071–5.668) | 0.167 | – | – | – |
HCV-Ab (+) | 1.060 | (0.138–8.148) | 0.955 | – | – | – |
Mode of transmission | 1.054 | (0.594–1.871) | 0.858 | – | – | – |
HIV subtype | 3.168 | (0.777–12.922) | 0.108 | – | – | – |
Resistance (low, intermediate and high) | 1.747 | (0.210–14.501) | 0.605 | – | – | – |