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Table 2 Laboratory and radiographic findings of the four cancer patients with SARS-CoV-2 infection

From: Clinical characteristics of four cancer patients with SARS-CoV-2 infection in Wuhan, China

Radiographic and laboratory findings

Normal Range

Case 1

Case 2

Case 3

Case 4

After admission

White blood cell count, × 109/L

3.5–9.5

4.21

10.91↑

4.86

5.46

Neutrophil count, × 109/L

1.8–6.3

2.05

4.11

3.8

3.53

Lymphocyte count, × 109/L

1.1–3.2

1.3

5.85

0.57↓

1.2

Hemoglobin, g/L

130–175

101↓

118↓

133

152

Platelet count, ×109/L

125–350

350

202

180

182

Procalcitonin, ng/mL

<  0.05

<  0.05

0.1↑

<  0.05

0.25

C-reactive protein, mg/L

0–10

NA

36.2↑

NA

NA

Abnormalities on chest X-ray/CT

No

No (Fig. 1a)

Bilateral patchy shadowing (Fig. 1d)

No (Fig. 1f)

No (Fig. 1k)

After fever onset

White blood cell count, ×109/L

3.5–9.5

2.86↓

6.67

2.7↓

9.36

Neutrophil count, ×109/L

1.8–6.3

1.79↓

3.55

1.21↓

8.73

Lymphocyte count, ×109/L

1.1–3.2

0.4↓

2.4

0.88↓

0.28↓

Hemoglobin, g/L

130–175

114↓

112↓

115↓

102↓

Platelet count, ×109/L

125–350

156

177

280

50↓

Procalcitonin, ng/mL

<  0.05

<  0.05

0.57↑

<  0.05

<  0.05

C-reactive protein, mg/L

0–10

0.7

77.9↑

1.3

18.1↑

Influenza A or B virus detection

Negative

Negative

Negative

Negative

Influenza A virus (+)

1–3-β-D polyglucosan (pg/ml)

(Neg.) < 60

(Pos.) > 110

NA

< 10

NA

165.7↑

Abnormalities on chest X-ray/CT

No

Interstitial abnormalities

(Fig. 1b)

Progress of bilateral lung diseases (Fig. 1e)

Local patchy shadowing (Fig. 1g)

Bilateral patchy shadowing (Fig. 1l)

Lymphocyte subsets (count/μl)

CD3+T cells

805–4459

435↓

297↓

865

335↓

CD3+CD4+T cells

345–2350

290↓

115↓

482

148↓

CD3+CD8+T cells

345–2350

142↓

184↓

341↓

185↓

B cells

240–1317

12↓

4213↑

44↓

41↓

NK cells

210–1514

59↓

132↓

154↓

43↓

Before discharge from hospital or dead

White blood cell count, ×109/L

3.5–9.5

3.12↓

16.52↑

4.04

6.28

Neutrophil count, ×109/L

1.8–6.3

2.18

7.37↑

2.22

5.34

Lymphocyte count, ×109/L

1.1–3.2

0.41↓

7.94↑

1.07↓

0.55↓

Hemoglobin, g/L

130–175

110.1↓

98.7↓

107.3↓

133.5

Platelet count, ×109/L

125–350

156

44↓

151

92↓

Procalcitonin, ng/ml

<  0.05

<  0.05

1.48↑

<  0.05

NA

C-reactive protein, mg/L

0–10

0.7

138.4↑

NA

NA

Detection of SARS-CoV-2 in throat swab samples

Dates of positive results

/

26 January

30 January

3 February

8 February

25 January

28 January

1 February

5 February

23 January

30 January

3 February

9 February

1 February

4 February

8 February

12 February

Negativity time of SARS-CoV-2a

/

13 February

/

15 February

10 March

  1. Abbreviations: SARS-CoV-2 severe acute respiratory syndrome coronavirus 2, NA not available, CT computed tomographic, NK cells natural killer cells
  2. aThe negativity time of SARS-CoV-2 was defined as the first day of a negative test if the nucleic acid of SARS-CoV-2 was negative for 2 consecutive tests (the sampling interval is at least 1 day)