|
Factors
|
Treatment outcomes at the last follow-up
|
Odds ratio (95% CI)
|
Adjusted odds ratio (95% CI) a
|
|---|
|
Favourable outcomes (n = 20)
|
Unfavourable outcomes (n = 36)
|
|---|
|
Age (mean±SD)
|
40.8 ± 16.8
|
49.1 ± 16.9
|
0.97 (0.94–1.00)
| |
|
Male
|
16 (80.0)
|
31 (86.1)
|
0.65 (0.15–2.74)
| |
|
Study sites in
|
|
Western
|
13 (65.0)
|
27 (75.0)
|
1
| |
|
Eastern
|
7 (35.0)
|
9 (25.0)
|
1.62 (0.49–5.30)
| |
|
Body mass index (mean±SD)
|
20.9 ± 2.0
|
20.0 ± 2.4
|
1.22 (0.94–1.58)
|
1.31 (0.99–1.75)
|
|
Education
|
|
Primary school or below
|
9 (45.0)
|
28 (77.8)
|
1
|
1
|
|
Junior high school or above
|
11 (55.0)
|
8 (22.2)
|
4.28 (1.31–13.9)
|
3.60 (1.04–12.5)
|
|
Married
|
13 (65.0)
|
17 (47.2)
|
2.08 (0.67–6.41)
|
1.66 (0.50–5.55)
|
|
Health insurance
|
19 (95.0)
|
30 (83.3)
|
3.80 (0.42–34.1)
|
4.54 (0.49–42.0)
|
|
Haemoptysis
|
4 (20.0)
|
11 (30.6)
|
0.57 (0.15–2.10)
|
0.59 (0.15–2.29)
|
|
Tuberculosis treatment history
|
6 (30.0)
|
18 (50.0)
|
0.43 (0.13–1.36)
|
0.43 (0.13–1.49)
|
|
Pulmonary cavities
|
12 (60.0)
|
15 (41.7)
|
2.10 (0.69–6.39)
|
1.92 (0.52–7.12)
|
|
DST pattern
|
|
MDR
|
12 (60.0)
|
18 (50.0)
|
1
|
1
|
|
Pre-XDR and XDR
|
8 (40.0)
|
18 (50.0)
|
0.67 (0.22–2.02)
|
0.87 (0.27–2.84)
|
|
Strain family (n = 50)
|
|
Non-Beijing family
|
2 (10.5)
|
4 (12.9)
|
1
|
1
|
|
Beijing family
|
17 (89.5)
|
27 (87.1)
|
1.26 (0.21–7.64)
|
1.58 (0.24–10.4)
|
|
Treatment regimen
|
|
Non-MDR-TB treatment
|
13 (65.0)
|
24 (66.7)
|
1
|
1
|
|
MDR-TB treatment
|
7 (35.0)
|
12 (33.3)
|
1.08 (0.34–3.40)
|
0.52 (0.13–2.10)
|
|
MDR-TB diagnosis delay (days)
|
|
≤ 90.0
|
13 (65.0)
|
18 (50.0)
|
1
|
1
|
|
> 90.0
|
7 (35.0)
|
18 (50.0)
|
0.54 (0.17–1.66)
|
0.44 (0.12–1.55)
|
- DNA was failure to extract from six Mycobacterium tuberculosis isolates. Two patients were once reported as treatment success but were lost at the last yearly follow-up, thus excluded from the analysis. MDR Multidrug-resistant, SD Standard deviation, DST Drug susceptibility testing, XDR Extensively drug-resistant
- aAdjusted by age, gender and study sites
