Table 2 Univariate and multivariate analysis of risk factors for unfavourable treatment outcomes among MDR-TB patients
Factors | Treatment outcomes at the last follow-up | Odds ratio (95% CI) | Adjusted odds ratio (95% CI) a | |
|---|---|---|---|---|
Favourable outcomes (n = 20) | Unfavourable outcomes (n = 36) | |||
Age (mean±SD) | 40.8 ± 16.8 | 49.1 ± 16.9 | 0.97 (0.94–1.00) | |
Male | 16 (80.0) | 31 (86.1) | 0.65 (0.15–2.74) | |
Study sites in | ||||
Western | 13 (65.0) | 27 (75.0) | 1 | |
Eastern | 7 (35.0) | 9 (25.0) | 1.62 (0.49–5.30) | |
Body mass index (mean±SD) | 20.9 ± 2.0 | 20.0 ± 2.4 | 1.22 (0.94–1.58) | 1.31 (0.99–1.75) |
Education | ||||
Primary school or below | 9 (45.0) | 28 (77.8) | 1 | 1 |
Junior high school or above | 11 (55.0) | 8 (22.2) | 4.28 (1.31–13.9) | 3.60 (1.04–12.5) |
Married | 13 (65.0) | 17 (47.2) | 2.08 (0.67–6.41) | 1.66 (0.50–5.55) |
Health insurance | 19 (95.0) | 30 (83.3) | 3.80 (0.42–34.1) | 4.54 (0.49–42.0) |
Haemoptysis | 4 (20.0) | 11 (30.6) | 0.57 (0.15–2.10) | 0.59 (0.15–2.29) |
Tuberculosis treatment history | 6 (30.0) | 18 (50.0) | 0.43 (0.13–1.36) | 0.43 (0.13–1.49) |
Pulmonary cavities | 12 (60.0) | 15 (41.7) | 2.10 (0.69–6.39) | 1.92 (0.52–7.12) |
DST pattern | ||||
MDR | 12 (60.0) | 18 (50.0) | 1 | 1 |
Pre-XDR and XDR | 8 (40.0) | 18 (50.0) | 0.67 (0.22–2.02) | 0.87 (0.27–2.84) |
Strain family (n = 50) | ||||
Non-Beijing family | 2 (10.5) | 4 (12.9) | 1 | 1 |
Beijing family | 17 (89.5) | 27 (87.1) | 1.26 (0.21–7.64) | 1.58 (0.24–10.4) |
Treatment regimen | ||||
Non-MDR-TB treatment | 13 (65.0) | 24 (66.7) | 1 | 1 |
MDR-TB treatment | 7 (35.0) | 12 (33.3) | 1.08 (0.34–3.40) | 0.52 (0.13–2.10) |
MDR-TB diagnosis delay (days) | ||||
≤ 90.0 | 13 (65.0) | 18 (50.0) | 1 | 1 |
> 90.0 | 7 (35.0) | 18 (50.0) | 0.54 (0.17–1.66) | 0.44 (0.12–1.55) |