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Table 1 Demographics, clinical characteristics and treatment of patients with COVID-19

From: Abnormal immunity of non-survivors with COVID-19: predictors for mortality

 

Total (539)

Non-survivor (125)

Survivor (414)

P value

Age (years)

58 (43–69)

70 (61.5–80)

54 (37–65)

< 0.0001

Gender

   

0.015

 Male

255 (47.3%)

71 (56.8%)

184 (44.4%)

 

 Female

284 (52.7%)

54 (43.2%)

230 (55.6%)

 

Chronic medical illness

242 (44.9%)

88 (70.4%)

154 (37.2%)

< 0.0001

Chronic obstructive lung disease

22 (4.1%)

12 (9.6%)

10 (2.4%)

< 0.0001

Diabetes

58 (10.9%)

25 (20.0%)

34 (8.2%)

< 0.0001

Hypertention

140 (26.0%)

62 (49.6%)

78 (18.8%)

< 0.0001

Coronary heart disease

37 (6.9%)

20 (16.0%)

17 (4.1%)

< 0.0001

Cerebrovascular diseases

19 (3.5%)

15 (12.0%)

4 (1.0%)

< 0.0001

Hepatitis

11 (2.0%)

3 (2.4%)

8 (1.9%)

0.746

Malignant tumour

23 (4.3%)

11 (8.8%)

12 (2.9%)

0.0042

Chronic kidney disease

8 (1.5%)

6 (4.8%)

2 (0.5%)

0.0005

Immunodeficiency disease

2 (0.4%)

0 (0.0%)

2 (0.5%)

0.436

Time from illness onset to death or discharge, days

13 (7–20)

7 (4–11)

15 (9–21)

< 0.0001

Signs and symptoms at admission

 Fever

420 (77.9%)

110 (88%)

310 (74.9)

0.001

 Rhinorrhoea

6 (1.1%)

2 (1.6%)

4 (1.0%)

0.945

 Cough

332 (61.6%)

81 (64.8%)

251 (60.6%)

0.402

 Expectoration

161 (29.9%)

48 (38.4%)

113 (27.3%)

0.017

 Chest tightness

187 (34.7%)

73 (58.4%)

114 (27.5%)

< 0.0001

 Dyspnea

187 (34.7%)

78 (62.4%)

98 (23.7%)

< 0.0001

 Fatigue

261 (48.4%)

78 (62.4%)

183 (44.2%)

< 0.0001

 Nausea

9 (1.7%)

5 (4.0%)

4 (1.0%)

0.02

 Diarrhea

58 (10.8%)

8 (6.4%)

50 (12.1%)

0.073

Clinical Classification

   

< 0.0001

 Non-severe

133 (24.7%)

2 (1.6%)

131 (31.6%)

 

 Severe

406 (75.3%)

123 (98.4%)

283 (68.4%)

 

Treatment

 Antibiotic drug

374 (69.4%)

118 (94.4%)

256 (61.8%)

< 0.0001

 Antiviral therapy or Chinese Medicine

225 (41.7%)

58 (46.4%)

167 (40.3%)

0.228

 Lianhua Qingwen

301 (55.8%)

40 (32.0%)

261 (63.0%)

<  0.0001

 Oseltamivir

157 (29.1%)

48 (38.4%)

109 (26.3%)

0.0092

 Arbidol

370 (68.6%)

65 (52.0%)

305 (73.7%)

< 0.0001

 Lopinavir/ritonavir

32 (5.9%)

18 (14.4%)

14 (3.4%)

< 0.0001

 Human immunoglobulin

250 (38.4%)

91 (72.8%)

159 (38.4%)

< 0.0001

 Alpha-interferon

170 (31.5%)

34 (27.2%)

136 (32.9%)

0.233

 Thymosin

59 (10.9%)

20 (16.0%)

39 (9.4%)

0.039

 Glucocorticoids

249 (46.2%)

89 (71.2%)

160 (38.6%)

< 0.0001

  1. Data are median (IQR) and n (%). P values were calculated by Mann-Whitney U test, χ2 test, or Fisher’s exact test, as appropriate. Statistical significance was determined at P<0.05
  2. COVID-19 Coronavirus disease 2019