Performance of a real-time PCR approach for diagnosing Schistosoma haematobium infections of different intensity in urine samples from Zanzibar

Table 2 Sensitivity and specificity of qPCR using urine filtration, reagent strips, or a combination of urine filtration and reagent strips as reference test for S. haematobium diagnosis in urine samples from Zanzibar

	Urine filtration	Negative	Positive	Total
qPCR	Negative	569	11	580
	Positive	118	94	212
	Total	687	105	792
	Sensitivity	89.5% (95% CI: 87.4–91.7%)
	Specificity	82.8% (95% CI: 80.2–85.5%)
	Reagent strips	Negative	Positive	Total
qPCR	Negative	557	23	580
	Positive	126	86	212
	Total	683	109	792
	Sensitivity	78.9% (95% CI: 76.1–81.7%)
	Specificity	81.6% (95% CI: 78.9–84.3%)
	Urine filtration plus reagent strips	Negative	Positive	Total
qPCR	Negative	553	27	580
	Positive	110	102	212
	Total	663	129	792
	Sensitivity	79.1% (95% CI: 76.2–81.9%)
	Specificity	83.4% (95% CI: 80.8–86.0%)

ISSN: 2049-9957